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Inapplicable"},{"orgOrder":0,"company":"Eisai","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"JAPAN","productType":"Vitamins\/Minerals\/Inorganic Salts","year":"2024","type":"Inapplicable","leadProduct":"Methylcobalamin","moa":"Undisclosed","graph1":"Neurology","graph2":"Phase III","graph3":"Eisai","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Eisai \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Eisai \/ Inapplicable"},{"orgOrder":0,"company":"Eisai","sponsor":"CNX Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"JAPAN","productType":"Other Small Molecule","year":"2024","type":"Divestment","leadProduct":"Loxapine Succinate","moa":"5-HT2C receptor","graph1":"Psychiatry\/Psychology","graph2":"Approved FDF","graph3":"Eisai","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Eisai \/ CNX Therapeutics","highestDevelopmentStatusID":"15","companyTruncated":"Eisai \/ CNX Therapeutics"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : BB-1701 is an HER2 inhibitor antibody-drug conjugate, which is currently being evaluated for the treatment of HER2-positive or HER2-low Unresectable or Metastatic Breast Cancer.

                          Product Name : BB-1701

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          March 21, 2025

                          Lead Product(s) : BB-1701

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Leqembi (lecanemab) is an IgG1 monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid-beta. It is being investigated for the treatment of early Alzheimer’s disease.

                          Product Name : Leqembi

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          December 04, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Leqembi (lecanemab) is an IgG1 monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid-beta. It is being investigated for the treatment of early Alzheimer’s disease.

                          Product Name : Leqembi

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 27, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Leqembi (lecanemab) selectively binds to soluble Aβ aggregates (protofibrils), as well as insoluble amyloid beta aggregates (fibrils) which are a major component of amyloid beta plaques in AD.

                          Product Name : Leqembi

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 14, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Biogen

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Leqembi (lecanemab-irmb) is a humanized IgG1 monoclonal antibody aimed at aggregated soluble and insoluble amyloid-beta forms, indicated for treating Alzheimer’s disease.

                          Product Name : Leqembi

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 01, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Biogen

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Leqembi (lecanemab) is an IgG1 monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta. It is indicated for the treatment of Alzheimer’s disease.

                          Product Name : Leqembi

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          October 31, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Leqembi (lecanemab), a humanized IgG1 monoclonal antibody directed against aggregated soluble & insoluble forms of amyloid-beta indicated for alzheimer’s disease.

                          Product Name : Leqembi

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          October 07, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Dotinurad, a novel urate transporter (URAT1) inhibitor for gout with potential to address other conditions associated with hyperuricemia such as chronic kidney disease.

                          Product Name : Urece

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 10, 2024

                          Lead Product(s) : Dotinurad

                          Therapeutic Area : Rheumatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : E2086 an oral novel selective orexin-2 agonist, being investigated for narcolepsy type I in adults. Nonclinical studies have demonstrated statistically significant reductions in rates of cataplexy.

                          Product Name : E2086

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 07, 2024

                          Lead Product(s) : E2086

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : The net proceeds will be used to evaluate the safety and efficacy profiles of next-generation cPheRS-inhibitor antimalarials, with potentially lower cost of treatment and improved safety profiles.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          August 05, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : The Global Health Innovative Technology

                          Deal Size : $0.7 million

                          Deal Type : Funding

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