Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : EIS-12656,Olaparib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : CPRIT
Deal Size : $4.7 million
Deal Type : Funding
Eisbach Bio Secures CPRIT Grant to Advance Novel Cancer Therapeutic
Details : The funds will support the clinical development of Eisbach's first-in-class allosteric small molecule inhibitor EIS-12656 targeting ALC1, to treat human cancers.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Undisclosed
November 26, 2024
Lead Product(s) : EIS-12656,Olaparib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : CPRIT
Deal Size : $4.7 million
Deal Type : Funding
Lead Product(s) : EIS-12656,Olaparib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eisbach Doses First Patient in Phase 1/2 Trial for EIS-12656 in Refractory Solid Tumors
Details : EIS-12656 targets ALC1 through allosteric mechanisms, suppressing the cancer-relevant genome reorganization induced by DNA damage. This leads to ALC1 chromatin trapping and cancer cell killing.
Product Name : EIS-12656
Product Type : Small molecule
Upfront Cash : Not Applicable
September 16, 2024
Lead Product(s) : EIS-12656,Olaparib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : EIS-12656
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eisbach Bio Announces FDA Clearance of IND Application for EIS-12656 Allosteric Inhibitor
Details : EIS-12656 targets ALC1 through allosteric mechanisms, suppressing the cancer-relevant genome reorganization induced by DNA damage. This leads to ALC1 chromatin trapping and cancer cell killing.
Product Name : EIS-12656
Product Type : Small molecule
Upfront Cash : Not Applicable
May 06, 2024
Lead Product(s) : EIS-12656
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable