Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : BVF Partners LP
Deal Size : $85.0 million
Deal Type : Public Offering
Eledon Pharmaceuticals Prices $85M Stock And Warrants Offering
Details : The proceeds from the offering will be used to advance its pipeline, which includes AT-1501 (tegoprubart), an experimental humanized monoclonal antibody, being evaluated for treating Organ Rejection.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : BVF Partners LP
Deal Size : $85.0 million
Deal Type : Public Offering
Lead Product(s) : Tegoprubart
Therapeutic Area : Endocrinology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eledon Reports Positive Tegoprubart Data in Islet Transplantation for Type 1 Diabetes
Details : The Company’s lead product is AT-1501 (tegoprubart), an anti-CD40L antibody with high affinity for the CD40 Ligand, a well-validated biological target that has broad therapeutic potential.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eledon Completes Enrollment in Ph 2 Trial for Tegoprubart in Kidney Transplant Patients
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 04, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eledon Provides Enrollment Update for Phase 2 Trial of Tegoprubart for Organ Rejection
Details : AT-1501 (tegoprubart), an anti-CD40L antibody with high affinity for the CD40 ligand, being developed for the prevention of rejection in kidney transplantation.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 29, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Leerink Partners
Deal Size : $50.0 million
Deal Type : Private Placement
Eledon Pharmaceuticals Announces Oversubscribed $50 Million Private Placement
Details : The company aims to develop AT-1501 (tegoprubart), a humanized monoclonal antibody targeting CD40L, for kidney transplantation.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 07, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Leerink Partners
Deal Size : $50.0 million
Deal Type : Private Placement
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eledon Announces Clinical Progress with Tegoprubart to Prevent Transplant Rejection
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 07, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eledon Enrolls 12th Participant in Phase 2 BESTOW Trial for Organ Rejection
Details : AT-1501 (tegoprubart) is an experimental humanized monoclonal antibody that inhibits CD40L. It is being evaluated for the treatment of Organ Rejection.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 25, 2024
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AT-1501 (tegoprubart) is an investigational, humanized IgG1 anti-CD40L antibody with high affinity for the CD40 ligand, which is investigated for the treatment of prevention of rejection in kidney transplantation.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 05, 2023
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The Company intends to use the net proceeds to fund the clinical development of its lead asset AT-1501 (tegoprubart), an anti-CD40L antibody with high affinity for CD40 Ligand.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : $35.0 million
May 01, 2023
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Study Phase : Preclinical
Recipient : eGenesis
Deal Size : Undisclosed
Deal Type : Collaboration
Details : AT-1501 (tegoprubart) is an investigational, humanized IgG1 anti-CD40L antibody with high affinity for the CD40 ligand. CD40L plays a pivotal role in immune system activation by mediating both antibody and cellular immune responses.
Brand Name : AT-1501
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 09, 2023
Lead Product(s) : Tegoprubart
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Recipient : eGenesis
Deal Size : Undisclosed
Deal Type : Collaboration
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