Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Kalaris Announces Closing of Merger with AlloVir
Details : The combined company will focus on the development of TH103, a fully humanized, recombinant fusion protein, for patients with neovascular age-related macular degeneration.
Product Name : TH103
Product Type : Protein
Upfront Cash : Undisclosed
March 18, 2025
Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Discovery Platform
Sponsor : Amazon Web Services
Deal Size : Undisclosed
Deal Type : Collaboration
ElevateBio, AWS Expand CRISPR Gene Editing with Generative AI
Details : The collaboration aims to accelerate the discovery and development of CRISPR gene editing therapeutics through AI for treating cancer and genetic diseases.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
March 10, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery Platform
Sponsor : Amazon Web Services
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : LETI-101
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ElevateBio Announces Compelling Preclinical Data of LETI-101 for Huntington's Disease
Details : LETI-101 is a selective reducer of disease-causing mutant huntingtin (mHTT) protein, It is being evaluated in patients with huntington's disease.
Product Name : LETI-101
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 24, 2025
Lead Product(s) : LETI-101
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
AlloVir & Kalaris Merge, Focus on Retinal Disease Therapies
Details : The combined company will focus on the development of TH103, a fully humanized, recombinant fusion protein, for patients with neovascular age-related macular degeneration.
Product Name : TH103
Product Type : Protein
Upfront Cash : Undisclosed
August 11, 2024
Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ALVR105 (posoleucel) is a T-lymphocyte cell therapy which is under phase 3 clinical development for the treatment of adenovirus infections, BK virus infections & Epstein-Barr virus infection.
Product Name : Viralym-M
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
December 22, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
AlloVir Announces Plans to Complete Enrollment in Three Phase 3 Posoleucel Studies in 2023
Details : Viralym-M (posoleucel) is a multi-virus specific T cell therapy (VST) targeting five viral pathogens ((BKV), (CMV), (AdV), (EBV), HHV-6). It is designed to play an important role in providing bridging immunity between conditioning and reconstitution of t...
Product Name : Viralym-M
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
September 01, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : J.P. Morgan
Deal Size : $7.5 million
Deal Type : Public Offering
AlloVir Announces Pricing of Public Offering of Common Stock
Details : The company intends to use the net proceeds to complete enrollment and achieve data readouts in all three of its ongoing Phase 3 trials of its lead multi-virus specific candidate, Viralym-M (posoleucel), an allogeneic, off-the-shelf multi-virus specific ...
Product Name : Viralym-M
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 21, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : J.P. Morgan
Deal Size : $7.5 million
Deal Type : Public Offering
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : AyurMaya Capital Management Fund
Deal Size : $401.0 million
Deal Type : Series D Financing
ElevateBio Announces $401 Million Series D Financing to Further Accelerate Growth
Details : The proceeds will advance the company’s technology platforms, Life Edit gene editing, iPSCs, and RNA, cell, protein, vector engineering and BaseCamp®, to accelerate the design, manufacturing, and development of cell and gene therapies.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
May 24, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : AyurMaya Capital Management Fund
Deal Size : $401.0 million
Deal Type : Series D Financing
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Viralym-M (posoleucel) is a multi-virus specific T cell therapy (VST) targeting five viral pathogens ((BKV), (CMV), (AdV), (EBV), HHV-6). It is designed to play an important role in providing bridging immunity between conditioning and reconstitution of t...
Product Name : Viralym-M
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
February 15, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Undisclosed
Sponsor : California Institute for Regenerative Medicine
Deal Size : Undisclosed
Deal Type : Partnership
Details : The partnership with CIRM reflects the novelty of the iPSC platform and recognition of next-generation cell lines that address industry challenges and could potentially save time and costs for partners developing iPSC-derived therapeutic.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 23, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Undisclosed
Sponsor : California Institute for Regenerative Medicine
Deal Size : Undisclosed
Deal Type : Partnership