Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
AlloVir & Kalaris Merge, Focus on Retinal Disease Therapies
Details : The combined company will focus on the development of TH103, a fully humanized, recombinant fusion protein, for patients with neovascular age-related macular degeneration.
Brand Name : TH103
Molecule Type : Large molecule
Upfront Cash : Undisclosed
November 08, 2024
Lead Product(s) : TH103
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Kalaris Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Recipient : Xcell Biosciences
Deal Size : Undisclosed
Deal Type : Collaboration
Xcell Collaborates with ElevateBio to Advance C&G Therapies Technology Development
Details : The collaboration aims to explore novel approaches to improve therapeutic potency of cell and gene therapies by leveraging Xcellbio’s AVATAR incubator system for cell therapy research and development.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 11, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Recipient : Xcell Biosciences
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ALVR105 (posoleucel) is a T-lymphocyte cell therapy which is under phase 3 clinical development for the treatment of adenovirus infections, BK virus infections & Epstein-Barr virus infection.
Brand Name : ALVR105
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 22, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : J.P. Morgan
Deal Size : $7.5 million
Deal Type : Public Offering
AlloVir Announces Pricing of Public Offering of Common Stock
Details : The company intends to use the net proceeds to complete enrollment and achieve data readouts in all three of its ongoing Phase 3 trials of its lead multi-virus specific candidate, Viralym-M (posoleucel), an allogeneic, off-the-shelf multi-virus specific ...
Brand Name : Viralym-M
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 21, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : J.P. Morgan
Deal Size : $7.5 million
Deal Type : Public Offering
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : AyurMaya Capital Management Fund
Deal Size : $401.0 million
Deal Type : Series D Financing
ElevateBio Announces $401 Million Series D Financing to Further Accelerate Growth
Details : The proceeds will advance the company’s technology platforms, Life Edit gene editing, iPSCs, and RNA, cell, protein, vector engineering and BaseCamp®, to accelerate the design, manufacturing, and development of cell and gene therapies.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
May 24, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : AyurMaya Capital Management Fund
Deal Size : $401.0 million
Deal Type : Series D Financing
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Viralym-M (posoleucel) is a multi-virus specific T cell therapy (VST) targeting five viral pathogens ((BKV), (CMV), (AdV), (EBV), HHV-6). It is designed to play an important role in providing bridging immunity between conditioning and reconstitution of t...
Brand Name : Viralym-M
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 15, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AlloVir Announces Plans to Complete Enrollment in Three Phase 3 Posoleucel Studies in 2023
Details : Viralym-M (posoleucel) is a multi-virus specific T cell therapy (VST) targeting five viral pathogens ((BKV), (CMV), (AdV), (EBV), HHV-6). It is designed to play an important role in providing bridging immunity between conditioning and reconstitution of t...
Brand Name : Viralym-M
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 09, 2023
Lead Product(s) : Posoleucel
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : TCR-engineered T Cell Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Affini-T Therapeutics
Deal Size : Undisclosed
Deal Type : Partnership
Details : Affini-T will leverage ElevateBio BaseCamp’s LentiPeak™ lentiviral vector technology platform and cell therapy production capabilities to advance its investigational oncogenic driver programs into clinical development.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 15, 2022
Lead Product(s) : TCR-engineered T Cell Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Affini-T Therapeutics
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : iPSC-based Therapeutic
Therapeutic Area : Technology
Study Phase : Undisclosed
Sponsor : California Institute for Regenerative Medicine
Deal Size : Undisclosed
Deal Type : Partnership
Details : The partnership with CIRM reflects the novelty of the iPSC platform and recognition of next-generation cell lines that address industry challenges and could potentially save time and costs for partners developing iPSC-derived therapeutic.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 23, 2022
Lead Product(s) : iPSC-based Therapeutic
Therapeutic Area : Technology
Highest Development Status : Undisclosed
Sponsor : California Institute for Regenerative Medicine
Deal Size : Undisclosed
Deal Type : Partnership
Details : Peer-reviewed publication in Cell Stem Cell unveils a novel differentiation process from develop mature immune cells from induced pluripotent stem cells (iPSCs), a potentially disruptive advantage in the development of allogeneic iPSC-derived immunothera...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
August 04, 2022
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