Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Elevation Oncology Gains Fast Track Designation for EO-3021 in Advanced Gastric Cancer
Details : EO-3021 is an ADC targeting Claudin 18.2. It is being evaluated for treatment of Claudin 18.2-expressing gastric, gastroesophageal junction, pancreatic or esophageal cancers.
Brand Name : EO-3021
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 23, 2024
Elevation Oncology Reports Promising Phase 1 Data for EO-3021 in Solid Tumors
Details : EO-3021 is an ADC targeting Claudin 18.2. It is being evaluated for treatment of Claudin 18.2-expressing gastric, gastroesophageal junction, pancreatic or esophageal cancers.
Brand Name : EO-3021
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 06, 2024
Elevation Oncology Plans Combination Strategy for EO-3021 in Gastric Cancer
Details : EO-3021 (SYSA1801) is an ADC targeting Claudin 18.2. It is being evaluated for treatment of Claudin 18.2-expressing gastric, gastroesophageal junction, pancreatic or esophageal cancers.
Brand Name : SYSA1801
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 27, 2024
Elevation Oncology Expands Phase 1 Trial of EO-3021, Dosing First Patient in Japan
Details : EO-3021 (SYSA1801), an antibody drug conjugate targeting Claudin 18.2, is under evaluation for advanced solid tumors likely to express Claudin 18.2, including gastric and pancreatic cancers.
Brand Name : SYSA1801
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 22, 2024
Elevation Oncology Announces First Patient Dosed in the Phase 1 Clinical Trial Evaluating EO-3021
Details : EO-3021 is a potential best-in-class antibody-drug conjugate that targets Claudin 18.2 evaluating patients with advanced unresectable or metastatic solid tumors likely to express Claudin 18.2 including gastric, gastroesophageal junction, pancreatic or es...
Brand Name : EO-3021
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 16, 2023
Lead Product(s) : SYSA1801
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : CSPC Pharmaceutical Group
Deal Size : $1,175.0 million
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Elevation Oncology will develop and commercialize EO-3021 in all global territories outside of Greater China. EO-3021 (also known as SYSA1801) is a differentiated, clinical stage antibody drug conjugate that targets Clau...
Brand Name : EO-3021
Molecule Type : Large molecule
Upfront Cash : $27.0 million
July 28, 2022
Lead Product(s) : SYSA1801
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : CSPC Pharmaceutical Group
Deal Size : $1,175.0 million
Deal Type : Licensing Agreement
Details : The response rate observed in Cohort 1 patient population, including complete and partial responses, together with early signs of durable responses and a well-tolerated safety profile, demonstrate the potential of MM-121 (seribantumab) to become a best-i...
Brand Name : MM-121
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 26, 2022
Details : Seribantumab is a fully human IgG2 monoclonal antibody that binds to human epidermal growth factor receptor 3 (HER3). HER3 is traditionally activated through binding of its primary ligand, neuregulin-1 (NRG1).
Brand Name : MM-121
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 27, 2022
Details : As of the data, treatment with seribantumab resulted in durable clinical benefit for over 9 months, an approximately 90% reduction in the cancer biomarker CA19-9, and an ongoing 3 month confirmed partial response per RECIST criteria with a maximum tumor ...
Brand Name : MM-121
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 14, 2021
Details : Seribantumab demonstrates significant activity in preclinical models through the destabilization of HER3 the & entire ERBB signaling pathway. These results are now being clinically evaluated in the PhII CRESTONE study for solid tumor patients harboring a...
Brand Name : MM-121
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 26, 2020
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