Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Elevation Stops EO-3021, Focuses on EO-1022 & Strategic Evaluations
Details : EO-3021 is an ADC targeting Claudin 18.2. It is being evaluated for treatment of Claudin 18.2-expressing gastric, gastroesophageal junction, pancreatic or esophageal cancers.
Product Name : EO-3021
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
March 20, 2025
Elevation Oncology Gains Fast Track Designation for EO-3021 in Advanced Gastric Cancer
Details : EO-3021 is an ADC targeting Claudin 18.2. It is being evaluated for treatment of Claudin 18.2-expressing gastric, gastroesophageal junction, pancreatic or esophageal cancers.
Product Name : EO-3021
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
September 23, 2024
Elevation Oncology Plans Combination Strategy for EO-3021 in Gastric Cancer
Details : EO-3021 (SYSA1801) is an ADC targeting Claudin 18.2. It is being evaluated for treatment of Claudin 18.2-expressing gastric, gastroesophageal junction, pancreatic or esophageal cancers.
Product Name : EO-3021
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
June 27, 2024
Elevation Oncology Reports Promising Phase 1 Data for EO-3021 in Solid Tumors
Details : EO-3021 is an ADC targeting Claudin 18.2. It is being evaluated for treatment of Claudin 18.2-expressing gastric, gastroesophageal junction, pancreatic or esophageal cancers.
Product Name : EO-3021
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
June 08, 2024
Elevation Oncology Expands Phase 1 Trial of EO-3021, Dosing First Patient in Japan
Details : EO-3021 (SYSA1801), an antibody drug conjugate targeting Claudin 18.2, is under evaluation for advanced solid tumors likely to express Claudin 18.2, including gastric and pancreatic cancers.
Product Name : EO-3021
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
February 22, 2024
Elevation Oncology Announces First Patient Dosed in the Phase 1 Clinical Trial Evaluating EO-3021
Details : EO-3021 is a potential best-in-class antibody-drug conjugate that targets Claudin 18.2 evaluating patients with advanced unresectable or metastatic solid tumors likely to express Claudin 18.2 including gastric, gastroesophageal junction, pancreatic or es...
Product Name : EO-3021
Product Type : Antibody-drug Conjugate
Upfront Cash : Inapplicable
August 16, 2023
Details : The response rate observed in Cohort 1 patient population, including complete and partial responses, together with early signs of durable responses and a well-tolerated safety profile, demonstrate the potential of MM-121 (seribantumab) to become a best-i...
Product Name : MM-121
Product Type : Antibody
Upfront Cash : Inapplicable
May 26, 2022
Details : Seribantumab is a fully human IgG2 monoclonal antibody that binds to human epidermal growth factor receptor 3 (HER3). HER3 is traditionally activated through binding of its primary ligand, neuregulin-1 (NRG1).
Product Name : MM-121
Product Type : Antibody
Upfront Cash : Inapplicable
April 27, 2022
Details : As of the data, treatment with seribantumab resulted in durable clinical benefit for over 9 months, an approximately 90% reduction in the cancer biomarker CA19-9, and an ongoing 3 month confirmed partial response per RECIST criteria with a maximum tumor ...
Product Name : MM-121
Product Type : Antibody
Upfront Cash : Inapplicable
October 14, 2021
Details : Seribantumab demonstrates significant activity in preclinical models through the destabilization of HER3 the & entire ERBB signaling pathway. These results are now being clinically evaluated in the PhII CRESTONE study for solid tumor patients harboring a...
Product Name : MM-121
Product Type : Antibody
Upfront Cash : Inapplicable
October 26, 2020