Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : EXG-34217
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Elixirgen Receives Rare Pediatric Designation for EXG-34217 in Dyskeratosis Congenita
Details : EXG-001, a non-integrating, non-transmissible, temperature-sensitive Sendai virus vector encoding human ZSCAN4, being evaluated for dyskeratosis congenita and related telomere biology disorders.
Brand Name : EXG-34217
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 25, 2024
Lead Product(s) : EXG-34217
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : EXG-5003
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EXG-5003, a SARS-CoV-2 vaccine developed with the Company’s temperature controllable self-replicating RNA (c-srRNA) technology. The data suggest a priming effect by EXG-5003 on the long-term cellular immunity of approved SARS-CoV-2 mRNA vaccines.
Brand Name : EXG-5003
Molecule Type : Vaccine
Upfront Cash : Not Applicable
October 16, 2023
Lead Product(s) : EXG-5003
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : EXG34217
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Hitachi Global Life Solutions
Deal Size : Undisclosed
Deal Type : Agreement
Details : Elixirgen Therapeutics is currently conducting a Phase 1/2 trial of EXG-34217, an autologous cell therapy to treat patients with telomere biology disorders with bone marrow failure. The collaboration with Hitachi would result in the development of Micro ...
Brand Name : EXG34217
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 26, 2023
Lead Product(s) : EXG34217
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Hitachi Global Life Solutions
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : EXG-34217,EXG-001
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EXG-34217 is an autologous cell therapy for telomere biology disorders with bone marrow failure that uses Elixirgen Therapeutics’ proprietary ZSCAN4 technology to extend the telomeres of the patients.
Brand Name : EXG-34217
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 07, 2022
Lead Product(s) : EXG-34217,EXG-001
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ZSCAN4-based Therapeutic
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Recipient : Taisho Pharmaceutical
Deal Size : Undisclosed
Deal Type : Partnership
Details : The partnership will leverage Elixirgen's proprietary ZSCAN4 therapy platform to advance treatments of aging-associated diseases. Elixirgen Therapeutics is currently performing a Phase I/II clinical trial using its ZSCAN4 therapy platform in disorders wi...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
March 07, 2022
Lead Product(s) : ZSCAN4-based Therapeutic
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Recipient : Taisho Pharmaceutical
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : EXG-5003
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Fujita Health University
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EXG-5003 is a temperature-sensitive self-replicating RNA vaccine expressing the receptor binding domain of the SARS-CoV-2 spike protein. EXG-5003 was optimized for intradermal injection with potential dose-sparing and safety benefits.
Brand Name : EXG-5003
Molecule Type : Vaccine
Upfront Cash : Not Applicable
September 01, 2020
Lead Product(s) : EXG-5003
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Fujita Health University
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : EXG-5003
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Elixirgen Therapeutics concluded on May 18 its pre-Investigational New Drug (pre-IND) meeting with the U.S. Food and Drug Administration (FDA) for the company's COVID-19 vaccine candidate, EXG-5003.
Brand Name : Undisclosed
Molecule Type : Vaccine
Upfront Cash : Not Applicable
June 04, 2020
Lead Product(s) : EXG-5003
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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