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[{"orgOrder":0,"company":"Cyan Bio","sponsor":"Adge Pharmaceuticals","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Adge Pharmaceuticals Partners with Cyan Bio of Korea to Advance Treatments for Rare Pediatric Diseases in Asian Countries","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase II","country":"SOUTH KOREA","productType":"Small molecule","productStatus":"New Molecular Entity","date":"April 2022","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase II"},{"orgOrder":0,"company":"F. Hoffmann-La Roche","sponsor":"Adge Pharmaceuticals","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Adge Pharmaceuticals Secures License To Evaluate Two New Programs In Rare Pediatric Diseases","therapeuticArea":"Musculoskeletal","highestDevelopmentStatus":"Preclinical","country":"SWITZERLAND","productType":"Small molecule","productStatus":"New Molecular Entity","date":"March 2022","url1":"","url2":"","graph1":"Musculoskeletal","graph2":"Preclinical"}]

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            Details:

            Adge has secured a global license to RO269228, a clinical stage oral small molecule originally developed by Roche for osteoporosis. RO269228, also known as elocalcitol, is a vitamin D analog which has demonstrated efficacy and safety in multiple Phase 2 clinical trials.

            Lead Product(s): Elocalcitol

            Therapeutic Area: Genetic Disease Product Name: RO269228

            Highest Development Status: Phase II Product Type: Small molecule

            Partner/Sponsor/Collaborator: Adge Pharmaceuticals

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership April 25, 2022

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            Adge Pharmaceuticals has in-licensed RO269228, a clinical stage oral small molecule, for the treatment of Rett syndrome and Osteogenesis imperfecta and potentially other indications with unmet medical needs.

            Lead Product(s): Elocalcitol

            Therapeutic Area: Musculoskeletal Product Name: RO269228

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Adge Pharmaceuticals

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement March 22, 2022

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