Lead Product(s) : Elraglusib,Gemcitabine,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Actuate Shows Positive Interim Data for Elraglusib in Metastatic Pancreatic Cancer
Details : 9-ING-41 (elraglusib), a novel GSK-3 inhibitor, targets molecular pathways in cancer that are involved in promoting tumor growth. It is being investigated for metastatic pancreatic cancer.
Brand Name : 9-ING-41
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 17, 2024
Lead Product(s) : Elraglusib,Gemcitabine,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Elraglusib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Actuate Receives FDA Rare Pediatric Disease Designation for Elraglusib
Details : 9-ING-41 (elraglusib), a novel GSK-3 inhibitor, targets molecular pathways in cancer that are involved in promoting tumor growth. It is being investigated for Ewing sarcoma.
Brand Name : 9-ING-41
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 12, 2024
Lead Product(s) : Elraglusib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Elraglusib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Actuate Receives FDA Orphan Drug Designation For Elraglusib in Sarcomas
Details : Actuate’s lead investigational drug product, 9-ING-41 (elraglusib), a novel GSK-3 inhibitor, targets molecular pathways in cancer that are involved in promoting tumor growth.
Brand Name : 9-ING-41
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 11, 2024
Lead Product(s) : Elraglusib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Elraglusib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Actuate Provides Update on Elraglusib Trial for Relapsed/Refractory Ewing Sarcoma
Details : Actuate’s lead investigational drug product, 9-ING-41 (elraglusib), a novel GSK-3 inhibitor, targets molecular pathways in cancer that are involved in promoting tumor growth.
Brand Name : 9-ING-41
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 09, 2024
Lead Product(s) : Elraglusib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Elraglusib,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : 9-ING-41 (elraglusib) is Actuate’s proprietary small molecule glycogen synthase kinase-3 beta (GSK-3β) inhibitor which is being developed for adults and children with advanced refractory pancreatic cancer cancer.
Brand Name : 9-ING-41
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 01, 2023
Lead Product(s) : Elraglusib,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Elraglusib,Retifanlimab,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Developmental Therapeutics Consortium
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : 9-ING-41 (elraglusib), a small molecule glycogen synthase kinase-3 beta combination Phase 2 trial with retifanlimab based on observed synergy with immune checkpoint inhibitors, and preclinical and early clinical data supporting immunomodulatory activity ...
Brand Name : 9-ING-41
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 01, 2022
Lead Product(s) : Elraglusib,Retifanlimab,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Developmental Therapeutics Consortium
Deal Size : Not Applicable
Deal Type : Not Applicable
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