2
ALL1
Bristol Myers Squibb1
Celgene CorporationYear
2
ALL1
20241
2020DEALS // DEV.
2
ALL2
DevelopmentsCountry
2
ALL2
U.S.A2
ALL1
AbbVie Inc1
InapplicableTherapeutic Area
2
ALL2
OncologyStudy Phase
2
ALL1
Approved FDF1
Phase I/ Phase IIDeal Type
2
ALL2
InapplicableProduct Type
2
ALL2
Other Small MoleculeDosage Form
2
ALL1
Oral Tablet1
Oral Tablet, Film CoatedLead Product
2
ALL2
EnasidenibTarget
2
ALL2
IDHLead Product(s) : Enasidenib,Venetoclax
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : AbbVie Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Enasidenib Plus Venetoclax Yields High Response Rates Targeting IDH2 Mutations in R/R AML
Details : Idhifa (enasidenib) is an isocitrate dehydrogenase-2 inhibitor, which is being evaluated in combination with venetoclax for the treatment of IDH2 gene mutated acute myeloid leukemia.
Product Name : Idhifa
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 02, 2024
Lead Product(s) : Enasidenib,Venetoclax
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : AbbVie Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Enasidenib,Hydroxyurea
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Phase 3 IDHENTIFY study evaluating IDHIFA®(enasidenib) plus best supportive care vs conventional care regimens, which include azacitidine plus BSC, low-dose cytarabine plus BSC or intermediate-dose cytarabine plus BSC, did not meet the primary endpoint.
Product Name : Idhifa
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 25, 2020
Lead Product(s) : Enasidenib,Hydroxyurea
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable