Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Enasidenib,Venetoclax
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : AbbVie Inc
Deal Size : Not Applicable
Deal Type : Not Applicable
Enasidenib Plus Venetoclax Yields High Response Rates Targeting IDH2 Mutations in R/R AML
Details : Idhifa (enasidenib) is an isocitrate dehydrogenase-2 inhibitor, which is being evaluated in combination with venetoclax for the treatment of IDH2 gene mutated acute myeloid leukemia.
Brand Name : Idhifa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 05, 2024
Lead Product(s) : Enasidenib,Venetoclax
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : AbbVie Inc
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Enasidenib,Hydroxyurea
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Phase 3 IDHENTIFY study evaluating IDHIFA®(enasidenib) plus best supportive care vs conventional care regimens, which include azacitidine plus BSC, low-dose cytarabine plus BSC or intermediate-dose cytarabine plus BSC, did not meet the primary endpoint.
Brand Name : Idhifa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 25, 2020
Lead Product(s) : Enasidenib,Hydroxyurea
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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