Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Processa Pharmaceuticals Announces First Patient Dosed in Phase 2 Trial of NGC-Cap
Details : PCS6422 is an analog of uracil that irreversibly inhibits dihydropyrimidine dehydrogenase (DPD) enzyme, being developed for the treatment of breast cancer.
Brand Name : PCS6422
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 02, 2024
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Processa Pharmaceuticals Announces FDA Clearance of NGC-Cap Phase 2 Trial in Breast Cancer
Details : PCS6422 is an analog of uracil that irreversibly inhibits dihydropyrimidine dehydrogenase (DPD) enzyme, being developed for the treatment of breast cancer.
Brand Name : PCS6422
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 30, 2024
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Processa Pharmaceuticals Reports Positive Phase 1b Results with NGC-Cap in Cancer
Details : NGC-Cap is PCS6422 (eniluracil) administered in combination with capecitabine, a precursor of the cancer drug 5-FU. It is being evaluated for the treatment of gastrointestinal cancer.
Brand Name : PCS6422
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 11, 2024
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $7.0 million
Deal Type : Public Offering
Processa Pharmaceuticals Announces Closing of $7.0 Million Public Offering
Details : The net proceeds will be used to advance the development of PCS6422 (eniluracil) administered in combination with capecitabine, for the treatment of advanced, refractory gastrointestinal tract tumors.
Brand Name : PCS6422
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 01, 2024
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $7.0 million
Deal Type : Public Offering
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Processa Completes Phase 1b Safety study of NGC-Cap Advanced Cancer, Recommends Phase 2
Details : NGC-Cap is PCS6422 (eniluracil) administered in combination with capecitabine, a precursor of the cancer drug 5-FU. It is being evaluated in phase 1 clinical trials for gastrointestinal cancer.
Brand Name : PCS6422
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 25, 2024
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Capecitabine,Eniluracil
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NGC-Cap combines the administration of PCS6422, the Company’s irreversible dihydropyrimidine dehydrogenase (DPD) enzyme inhibitor, with the administration of low doses of the commonly used chemotherapy capecitabine.
Brand Name : NGC-Cap
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 19, 2023
Lead Product(s) : Capecitabine,Eniluracil
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Processa Pharmaceuticals
Deal Size : $103.1 million
Deal Type : Licensing Agreement
Processa Pharmaceutical Enters Licensing Agreement with Elion Oncology
Details : PCS6422 is an oral drug to be administered with fluoropyrimidine cancer drugs to decrease the breakdown of the cancer drug to inactive metabolites or metabolites that are known to cause unwanted side effects and to interfere with the anticancer activity.
Brand Name : PCS6422
Molecule Type : Small molecule
Upfront Cash : $88.0 million
August 27, 2020
Lead Product(s) : Eniluracil,Capecitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Processa Pharmaceuticals
Deal Size : $103.1 million
Deal Type : Licensing Agreement
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