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Securities"}]

Find Clinical Drug Pipeline Developments & Deals for Enkephalin

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                          Top Deals by Deal Size (USD bn)

                          01

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : The net proceeds will used to fund the clinical development of Envelta (enkephalin), which is being evaluated for the treatment of neoplasms.

                          Product Name : Envelta

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 30, 2025

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Spartan Capital Securities

                          Deal Size : $6.0 million

                          Deal Type : Public Offering

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                          02

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : The net proceeds will used to fund the clinical development of Envelta (enkephalin), which is being evaluated for the treatment of neoplasms.

                          Product Name : Envelta

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 28, 2025

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Spartan Capital Securities

                          Deal Size : $6.0 million

                          Deal Type : Public Offering

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                          03

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : The collaboration aims for the continued development of Virpax’s product candidate, NES100 (leucine enkephalin), an intranasal peptide, for the management of acute and chronic non-cancer pain.

                          Product Name : NES100

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          November 21, 2024

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : NCATS

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : Envelta (MET-LENK) is a non-addictive intranasal molecular envelope endogenous enkephalin formulation being developed to manage acute and chronic pain, including pain associated with cancer.

                          Product Name : Envelta

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 31, 2023

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : Envelta™ is an intranasal molecular envelope endogenous enkephalin formulation being developed to manage acute and chronic pain, including pain associated with cancer.

                          Product Name : Envelta

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 13, 2023

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : Envelta is an investigational intranasal formulation intended to improve enkephalin transport to the brain. Envelta uses a preassembled device and cartridge to propel the enkephalin formulation through the nose to the brain by flowing along the olfactory...

                          Product Name : Envelta

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          February 10, 2022

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : The NIH has contracted with a clinical research organization to conduct additional pre-clinical efficacy studies for Envelta and procured a device to be used with the manufactured GMP drug product for preclinical and clinical studies.

                          Product Name : Envelta

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          November 10, 2021

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : National Institutes of Health

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          08

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : Under terms of the new contract, the company will support CMC's of NES-100, a microparticle dosage form of leu-enkephalin (LENK) that is prepared by the encapsulation of LENK in a patent-protected molecular enveloped technology and delivered via a nasal ...

                          Product Name : NES-100

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          October 20, 2021

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : National Institutes of Health

                          Deal Size : Undisclosed

                          Deal Type : Funding

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                          09

                          Natural Products Expo
                          Not Confirmed
                          Natural Products Expo
                          Not Confirmed

                          Details : Envelta™ is an investigational intranasal formulation intended to improve enkephalin transport to the brain. Enkephalin is a naturally occurring (endogenous) peptide that is not easily administered in its original form.

                          Product Name : Envelta

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          June 21, 2021

                          Lead Product(s) : Enkephalin

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : National Center for Advancing Translational Sciences

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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