Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ENT-03
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Enterin Announces the Start of a First-in-Human Study of ENT-03 in Obesity and Type 2 Diabetes
Details : ENT-03 is a novel, endogenous, centrally acting aminosterol with protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, which normalizes glucose and causes weight loss by acting on brain circuits that regulate energy and metabolism in Obesity and T...
Brand Name : ENT-03
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 05, 2023
Lead Product(s) : ENT-03
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Squalamine phosphate
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Enterin’s oral lead compound, ENT-01 which prevents alpha synuclein from accumulating and aggregating within the enteric nervous system, receives FDA acceptance of an investigator sponsored IND application to treat a patient with prodromal multisystem ...
Brand Name : ENT-01
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 31, 2023
Lead Product(s) : Squalamine phosphate
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Enterin and Parkinson’s UK Announce Research Collaboration in Parkinson’s Dementia
Details : ENT-01 is administered orally and acts locally on the ENS. It dislodges αS aggregates and inhibits their formation, restoring the firing potential of enteric neurons.
Brand Name : ENT-01
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 13, 2022
Lead Product(s) : ENT-01
Therapeutic Area : Neurology
Study Phase : Phase II
Recipient : Pfizer CentreOne
Deal Size : Undisclosed
Deal Type : Collaboration
How Creative Chemistry and Collaboration Synthesized a Better Drug Strategy For Enterin
Details : Enterin completed the first human clinical trials for ENT-01 which demonstrated that oral administration of its treatment has restored function of the nervous system of the gastrointestinal tract in Parkinson’s patients.
Brand Name : ENT-01
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 28, 2022
Lead Product(s) : ENT-01
Therapeutic Area : Neurology
Highest Development Status : Phase II
Recipient : Pfizer CentreOne
Deal Size : Undisclosed
Deal Type : Collaboration
Enterin to Present at Chardan's Virtual 3rd Annual Microbiome Medicines Summit
Details : Dr. Denise Barbut, Enterin's co-founder and CMO, will present the company's latest updates relating to its lead compound, ENT-01, which is currently being developed for the treatment of Parkinson's Disease (PD).
Brand Name : ENT-01
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 01, 2021
Lead Product(s) : COV-ENT-1
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Enterin to Conduct a Randomized Phase 1/2a Study in Hospitalized Patients With COVID-19
Details : COV-ENT-1 has been shown to have broad-spectrum antiviral activity against both RNA and DNA viruses, both in vitro and in vivo, in studies supported by the NIAID.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 17, 2020
Lead Product(s) : COV-ENT-1
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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