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                          01

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                          Details : Ent001 targets the TMEM219 ligand, IGFBP3, it is designed to bind to TMEM219 and prevent cell death and the inflammation in type 1 diabetes and several other autoimmune diseases.

                          Brand Name : Ent001

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 07, 2023

                          Lead Product(s) : Ent001

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

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                          Details : The proceeds from the Series A financing will be used to obtain clinical proof-of-concept through a first-in-human study of Ent001, Enthera’s lead candidate.

                          Brand Name : Ent001

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 28, 2021

                          Lead Product(s) : Ent001

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Preclinical

                          Sponsor : Roche Venture Fund

                          Deal Size : $42.3 million

                          Deal Type : Series A Financing

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                          03

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                          Details : Proceeds to be used for clinical proof-of-concept for lead product Ent001 (IGFBP3/TMEM219 inhibitor) for type 1 diabetes, gastrointestinal diseases and progress pipeline assets.

                          Brand Name : Ent001

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          July 28, 2020

                          Lead Product(s) : Ent001

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Preclinical

                          Sponsor : Sofinnova Partners

                          Deal Size : $33.1 million

                          Deal Type : Series A Financing

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