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    Find Clinical Drug Pipeline Developments & Deals by Entrada Therapeutics

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                            01

                            Entrada Therapeutics

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                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Janus Henderson Investors

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Entrada Therapeutics Announces $100 Million Registered Direct Offering

                            Details : Entrada expects to use the net proceeds from the offering to fund the ongoing clinical development of each of ENTR-601-44, which is being evaluated for the treatment of Duchenne Muscular Dystrophy.

                            Brand Name : ENTR-601-44

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 24, 2024

                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Janus Henderson Investors

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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                            02

                            Entrada Therapeutics

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                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Entrada Reports Preliminary Data from Phase 1 ENTR-601-44-101 Trial for DMD

                            Details : NTR-601-44, a proprietary EEV-conjugated phosphorodiamidate morpholino oligomer, which is an investigational therapy for the potential treatment of people living with Duchenne muscular dystrophy.

                            Brand Name : ENTR-601-44

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 24, 2024

                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Entrada Therapeutics

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                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Entrada Therapeutics Announces Updates on ENTR-601-44 in Duchenne Muscular Dystrophy

                            Details : ENTR-601-44, a proprietary Endosomal Escape Vehicle (EEV™)-conjugated phosphorodiamidate morpholino oligomer (PMO), is the lead product candidate within Entrada’s Duchenne muscular dystrophy franchise.

                            Brand Name : ENTR-601-44

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 22, 2023

                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Entrada Therapeutics

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                            Entrada Therapeutics

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                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Entrada Therapeutics Announces First Participant Dosed in its Phase 1 Clinical Trial of ENTR-601-44 for the Po...

                            Details : ENTR-601-44, a proprietary Endosomal Escape Vehicle (EEV™)-conjugated phosphorodiamidate morpholino oligomer (PMO), is the lead product candidate within its Duchenne franchise from Entrada’s growing pipeline of EEV-therapeutics.

                            Brand Name : ENTR-601-44

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 21, 2023

                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Entrada Therapeutics

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                            Entrada Therapeutics

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                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Entrada Therapeutics Receives Authorization in the United Kingdom to Initiate Phase 1 Clinical Trial of ENTR-6...

                            Details : ENTR-601-44, a proprietary Endosomal Escape Vehicle (EEV™)-conjugated phosphorodiamidate morpholino oligomer (PMO), is the lead product candidate within its Duchenne franchise from Entrada’s growing pipeline of EEV-therapeutics.

                            Brand Name : ENTR-601-44

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 01, 2023

                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Entrada Therapeutics

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                            Lead Product(s) : EEV-conjugated Phosphorodiamidate Morpholino Oligomer

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $735.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Entrada Therapeutics Closes Agreement with Vertex to Discover and Develop Endosomal Escape Vehicle-Therapeutic...

                            Details : The agreement includes a four-year global research collaboration whereby Entrada will continue to advance for certain research activities related to ENTR-701 (EEV-conjugated phosphorodiamidate morpholino oligomer), as well as additional DM1-related resea...

                            Brand Name : ENTR-701

                            Molecule Type : Large molecule

                            Upfront Cash : $224.0 million

                            February 09, 2023

                            Lead Product(s) : EEV-conjugated Phosphorodiamidate Morpholino Oligomer

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $735.0 million

                            Deal Type : Agreement

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                            07

                            Entrada Therapeutics

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                            Entrada Therapeutics

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                            Lead Product(s) : ENTR-601-45

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Entrada Therapeutics Announces Clinical Candidate, ENTR-601-45, for the Potential Treatment of People Living w...

                            Details : ENTR-601-45 is a Endosomal Escape Vehicle-conjugated phosphorodiamidate morpholino oligomer, has the potential to restore the mRNA reading frame and allow for the translation of dystrophin protein, it Duchenne muscular dystrophy patients.

                            Brand Name : ENTR-601-45

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 09, 2023

                            Lead Product(s) : ENTR-601-45

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Entrada Therapeutics

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                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Entrada Therapeutics Announces Clinical Hold on IND Application for ENTR-601-44 in Duchenne Muscular Dystrophy

                            Details : The Company’s lead oligonucleotide programs include ENTR-601-44 targeting Duchenne muscular dystrophy (DMD) and ENTR-701 targeting myotonic dystrophy type 1 (DM1).

                            Brand Name : ENTR-601-44

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 19, 2022

                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Entrada Therapeutics

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                            Entrada Therapeutics

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                            Lead Product(s) : EEV-conjugated Phosphorodiamidate Morpholino Oligomer

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $735.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Vertex and Entrada Therapeutics Establish Collaboration to Discover and Develop Endosomal Escape Vehicle (EEV)...

                            Details : ENTR-701, a proprietary Endosomal Escape Vehicle (EEV™)-conjugated phosphorodiamidate morpholino oligomer, is the second novel clinical candidate from Entrada’s growing pipeline of EEV therapeutics.

                            Brand Name : ENTR-701

                            Molecule Type : Large molecule

                            Upfront Cash : $224.0 million

                            December 08, 2022

                            Lead Product(s) : EEV-conjugated Phosphorodiamidate Morpholino Oligomer

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $735.0 million

                            Deal Type : Collaboration

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                            10

                            Entrada Therapeutics

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                            Entrada Therapeutics

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                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Entrada Therapeutics Presents New Data Supporting its Growing Pipeline of Endosomal Escape Vehicle (EEV) Thera...

                            Details : New non-human primate data demonstrate a durability of response through 12 weeks for lead clinical candidate, ENTR-601-44, for the potential treatment of Duchenne muscular dystrophy.

                            Brand Name : ENTR-601-44

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 11, 2022

                            Lead Product(s) : ENTR-601-44

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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