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Find Clinical Drug Pipeline Developments & Deals for Envafolimab
KN035 is an investigational PD-L1 antibody, which is currently being evaluated for the treatment of undifferentiated pleomorphic sarcoma & myxofibrosarcoma.
Glenmark will be responsible for further developing, registering, and commercializing KN035 (envafolimab), approved in China for the treatment of adult patients with previously treated MSI-H or dMMR advanced solid tumor, in multiple geographies around the World.
KN035 (envafolimab) is a single-domain antibody against PD-L1. It isbeing evaluated in phase 2 clinical trials for the treatment of undifferentiated pleomorphic sarcoma & myxofibrosarcoma.
ASC22 (envafolimab) is the signal transmission to T cells and promotes T cell activation by blocking both PD-1/PD-L1 and PD-L1/cluster of differentiation 80 (CD80) signaling pathways, which is investigated for chronic hepatitis b.
KN035 (envafolimab) is a single-domain antibody against PD-L1 invented by Alphamab Oncology and licensed by TRACON, is the first approved subcutaneously injected PD-(L)1 inhibitor, which is investigated for MSI-H/dMMR advanced solid tumors.
KN035 (envafolimab) is a single-domain antibody against PD-L1 invented by Alphamab Oncology and licensed by TRACON, is the first approved subcutaneously injected PD-(L)1 inhibitor, which is investigated for MSI-H/dMMR advanced solid tumors.
ASC22 (envafolimab) shows anti-tumor activity by blocking inhibitory signal transmission to T cells and promotes T cell activation by blocking both PD-1/PD-L1 and PD-L1/cluster of differentiation 80 (CD80) signaling pathways.
Envafolimab (KN035), a single-domain antibody against PD-L1 invented by Alphamab Oncology and licensed by TRACON, is the first approved subcutaneously injected PD-(L)1 inhibitor.
YH001 is an IgG1 antibody against CTLA-4 that has shown enhanced antibody dependent cellular cytotoxicity and complement dependent cytotoxicity in vitro. YH001 demonstrated superior T cell activation and superior tumor growth inhibition activity compared to ipilimumab.
Envafolimab (KN035), a single-domain antibody against PD-L1 is the first approved subcutaneously injected PD-(L)1 inhibitor. Envafolimab is currently being studied in the ENVASARC Phase 2 and a Phase 3 pivotal trial in advanced biliary tract cancer patients.
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