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Therapeutics","pharmaFlowCategory":"D","amount":"$66.5 million","upfrontCash":"Undisclosed","newsHeadline":"Enveric Biosciences Signs $66.5 Million Term Sheet with MindBio for Psilocin Prodrug","therapeuticArea":"Psychiatry\/Psychology","highestDevelopmentStatus":"Preclinical","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"May 2024","url1":"","url2":"","graph1":"Psychiatry\/Psychology","graph2":"Preclinical"}]

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            Details:

            EB-003 is a novel 5-HT2A receptor agonist which is currently being evaluated in preclinical studies for the treatment of depression and anxiety disorders.

            Lead Product(s): EB-003

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-003

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 25, 2024

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            MindBio will seek to advance a drug candidate EB-002 (Psilocin Prodrug). Currently, it is being evaluated in the early-stage clinical trials studies for the treatment of depression, anxiety.

            Lead Product(s): Psilocin Prodrug

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-002

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: MindBio Therapeutics

            Deal Size: $66.5 million Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement May 14, 2024

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            Enveric plans to continue to focus and invest in the development of its lead candidates EB-003, a first-in-class neuroplastogen designed to eliminate hallucinations, and EB-002, formerly EB-373, a next generation synthetic prodrug of the active metabolite, psilocin.

            Lead Product(s): EB-003

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-003

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Undisclosed

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Divestment January 23, 2024

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            EB-003 is a novel 5-HT2A receptor agonist which is currently being evaluated in preclinical studies for the treatment of depression and anxiety disorders.

            Lead Product(s): EB-003

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-003

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 03, 2024

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            EB-373 (psilocybin prodrug) is an oral 5-HT2A receptor agonist. It is being evaluated in preclinical studies for the treatment of generalized anxiety disorder.

            Lead Product(s): Psilocybin Prodrug

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-373

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 27, 2023

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            Enveric lead product candidate EVM301, which is a 5-HT2A receptor modulator small molecule drug candidate. It is being evaluated for the treatment of anxiety.

            Lead Product(s): EVM301

            Therapeutic Area: Psychiatry/Psychology Product Name: EVM301

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 05, 2023

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            Details:

            EB-373, is a new chemical entity (NCE), designed as a next-generation proprietary psilocin prodrug and developed leveraging the company’s Psybrary™ drug discovery platform to target psychiatric disorders.

            Lead Product(s): Psilocin Prodrug

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-373

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 18, 2023

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            Details:

            EB-373, is a new chemical entity (NCE), designed as a next-generation proprietary psilocin prodrug and developed leveraging the company’s Psybrary™ drug discovery platform to target anxiety disorders.

            Lead Product(s): Psilocin Prodrug

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-373

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 21, 2023

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            Details:

            EB-373, is a New Chemical Entity (NCE), designed as a next-generation proprietary psilocin prodrug and developed leveraging the company’s Psybrary™ drug discovery platform to target anxiety disorders.

            Lead Product(s): Psilocin Prodrug

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-373

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 24, 2023

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            Details:

            EB-373 is a New Chemical Entity (NCE), designed as a next-generation proprietary psilocin prodrug and developed by leveraging its Psybrary™ drug discovery platform to target anxiety disorders.

            Lead Product(s): Psilocybin Prodrug

            Therapeutic Area: Psychiatry/Psychology Product Name: EB-373

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 17, 2023

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