Lead Product(s) : Epicatechin
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Epirium Bio Announces Commencement of Phase 1 Clinical Trial of EPM-01 in Becker Muscular Dystrophy
Details : The Phase 1 open-label, dose-escalation study is evaluating the safety, preliminary clinical efficacy and potential biomarkers of three doses of EPM-01 in participants with Becker or Becker-like muscular dystrophy.
Product Name : EPM-01
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 08, 2020
Lead Product(s) : Epicatechin
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Epicatechin
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Epirium
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Epirium has advanced its first clinical candidate EPM-01 (Epicatechin) in Becker muscular dystrophy and plans to follow with drug development targeting other disorders associated with mitochondrial dysfunction and tissue degeneration.
Product Name : EPM-01
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
August 27, 2020
Lead Product(s) : Epicatechin
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Epirium
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Epicatechin
Therapeutic Area : Genetic Disease
Study Phase : Undisclosed
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The company's prior studies have shown that EB 002 can stimulate mitochondrial biogenesis, contributing to the restoration of tissue bioenergetics, thus upregulating key protein production.
Product Name : EPM-01
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 14, 2020
Lead Product(s) : Epicatechin
Therapeutic Area : Genetic Disease
Highest Development Status : Undisclosed
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable