Lead Product(s) : Epicatechin
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Epirium
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Epirium has advanced its first clinical candidate EPM-01 (Epicatechin) in Becker muscular dystrophy and plans to follow with drug development targeting other disorders associated with mitochondrial dysfunction and tissue degeneration.
Brand Name : EPM-01
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 27, 2020
Lead Product(s) : Epicatechin
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Epirium
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Epicatechin
Therapeutic Area : Musculoskeletal
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Epirium Bio Announces Commencement of Phase 1 Clinical Trial of EPM-01 in Becker Muscular Dystrophy
Details : The Phase 1 open-label, dose-escalation study is evaluating the safety, preliminary clinical efficacy and potential biomarkers of three doses of EPM-01 in participants with Becker or Becker-like muscular dystrophy.
Brand Name : EPM-01
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 12, 2020
Lead Product(s) : Epicatechin
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Epicatechin
Therapeutic Area : Musculoskeletal
Study Phase : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The company's prior studies have shown that EB 002 can stimulate mitochondrial biogenesis, contributing to the restoration of tissue bioenergetics, thus upregulating key protein production.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 14, 2020
Lead Product(s) : Epicatechin
Therapeutic Area : Musculoskeletal
Highest Development Status : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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