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Find Clinical Drug Pipeline Developments & Deals for Eptinezumab

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                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The safety of Eptinezumab-jjmr was evaluated in 2,076 patients with migraine who received at least one dose of VYEPTI. The most common adverse reactions in the clinical trials for the preventive treatment of migraine were nasopharyngitis and hypersensiti...

                          Brand Name : Vyepti

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 09, 2022

                          Lead Product(s) : Eptinezumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Poster presentation of exploratory analysis from PROMISE 2 showed VYEPTI was associated with greater declines in headache frequency and days of acute headache medication use vs. placebo in people dually diagnosed with chronic migraine and medication over...

                          Brand Name : Vyepti

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 02, 2022

                          Lead Product(s) : Eptinezumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Vyepti is a humanized monoclonal antibody that binds to CGRP which was purposefully developed for IV administration met its primary endpoint of decrease in MMDs over weeks 1-12 in both episodic and chronic migraine.

                          Brand Name : Vyepti

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 01, 2021

                          Lead Product(s) : Eptinezumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Patients receiving VYEPTI reported a median time to headache pain freedom of 4 hours vs. 9 hours among those who received placebo, and a median time of 2 hours to the absence of their MBS vs. 3 hours with placebo.

                          Brand Name : Vyepti

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 15, 2021

                          Lead Product(s) : Eptinezumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : VYEPTI met its primary endpoint of decrease in mean monthly migraine days (MMD) over months 1-3 in both episodic and chronic migraine. The safety of VYEPTI was evaluated in 2,076 patients with migraine who received at least one dose of VYEPTI.

                          Brand Name : Vyepti

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 03, 2021

                          Lead Product(s) : Eptinezumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Post-hoc closed testing analysis suggests onset of a migraine preventive effect with intravenous VYEPTI as early as day 1 following the initial dose.

                          Brand Name : Vyepti

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 13, 2020

                          Lead Product(s) : Eptinezumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Orsini Pharmaceutical has been selected as one of a very limited number of distribution partners for VYEPTI™ (eptinezumab-jjmr).

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 22, 2020

                          Lead Product(s) : Eptinezumab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Orsini Specialty Pharmacy

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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