Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : RMC-6236
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Revolution Medicines
Deal Size : Undisclosed
Deal Type : Acquisition
Revolution Medicines Completes Acquisition of EQRx
Details : Through the acquisition, Revolution expects to conduct late-stage development of RAS(ON) inhibitor drug candidate pipeline, including RMC-6236, in multiple RAS-driven cancers.
Brand Name : RMC-6236
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 09, 2023
Lead Product(s) : RMC-6236
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Revolution Medicines
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : RMC-6236
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Revolution Medicines
Deal Size : Undisclosed
Deal Type : Acquisition
Details : Through the acquisition, Revolution expects to conduct late-stage development of RAS(ON) inhibitor drug candidate pipeline, including RMC-6236, in multiple RAS-driven cancers.
Brand Name : RMC-6236
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 01, 2023
Lead Product(s) : RMC-6236
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Revolution Medicines
Deal Size : Undisclosed
Deal Type : Acquisition
Details : Under the terms of the collaboration agreement, Aurigene will lead drug discovery and pre-clinical development efforts, and EQRx will assume responsibility for clinical development, manufacturing, regulatory and commercialization efforts.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 05, 2022
Lead Product(s) : Aumolertinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
EQRx Announces New Data on Lead Oncology Programs to Be Presented at 2022 ASCO Annual Meeting
Details : Aumolertinib is a third-generation, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that targets both EGFR- sensitizing and T790M resistance mutations, with high selectivity over wild-type EGFR.
Brand Name : EQ143
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 29, 2022
Lead Product(s) : Aumolertinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : Insilico Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration will combine Insilico's Pharma.AI platform to advance de novo small molecule design and generation with EQRx's clinical development and commercialization expertise.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 24, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : Insilico Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Aumolertinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Abdul Latif Jameel Health
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Through the agreement, Abdul Latif Jameel Health will become EQRx’s regulatory and commercial partner for aumolertinib and sugemalimab, if approved, in selected markets throughout the Middle East region, as well as in Turkey and all of Africa.
Brand Name : EQ143
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 22, 2021
Lead Product(s) : Aumolertinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Abdul Latif Jameel Health
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Aumolertinib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : CM Life Sciences
Deal Size : $2,000.0 million
Deal Type : Merger
Details : Proceeds expand balance sheet to ~$2.0 billion and will be used for “new pharma” platforms. EQRx’s growing pipeline includes two pre-registrational oncology assets that have shown promising Phase 3 data (aumolertinib and sugemalimab), and other cli...
Brand Name : EQ143
Molecule Type : Small molecule
Upfront Cash : $2,000.0 million
August 06, 2021
Lead Product(s) : Aumolertinib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : CM Life Sciences
Deal Size : $2,000.0 million
Deal Type : Merger
Lead Product(s) : Sugemalimab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : CStone Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : GEMSTONE-301 study investigating sugemalimab as consolidation therapy in patients with locally advanced, unresectable Stage III NSCLC without disease progression after either concurrent or sequential chemoradiotherapy.
Brand Name : CS1001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 28, 2021
Lead Product(s) : Sugemalimab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : CStone Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sugemalimab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : $500.0 million
Deal Type : Series B Financing
Details : Funding accelerates development of late-stage cancer therapies which includes sugemalimab, almonertinib, EQRx’s PD-1 antibody (formerly known as CS1003) and lerociclib, a CDK4/6 inhibitor.
Brand Name : CS1001
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 11, 2021
Lead Product(s) : Sugemalimab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : $500.0 million
Deal Type : Series B Financing
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