Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Erytech Pharma
Deal Size : Undisclosed
Deal Type : Merger
Details : Strategic combination will accelerate development of extended phage therapies for antimicrobial resistance including Anti-Staphylococcus aureus Bacteriophages, in particular via the phase II PhagoDAIR study conducted by PHERECYDES.
Product Name : Undisclosed
Product Type : Microorganism
Upfront Cash : Undisclosed
February 15, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Erytech Pharma
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Eryaspase
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ERYTECH Provides Regulatory Update
Details : In multiple clinical trials, Graspa (erythrocytes encapsulating L-asparaginase) showed promising results for patients, in hypersensitive acute lymphoblastic leukemia (ALL) to pegylated asparaginase therapy.
Product Name : Graspa
Product Type : Enzyme
Upfront Cash : Inapplicable
August 24, 2022
Lead Product(s) : Eryaspase
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Red Blood Cell-Encapsulated Arginine Deiminase
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ERYTECH Expands Patent Portfolio for the Treatment of Rare Metabolic Diseases
Details : US patent application for Enzyme replacement therapy cover arginine deiminase encapsulated into red blood cells for the treatment of arginase-1 deficiency (A1D), a debilitating rare metabolic disease.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
August 02, 2022
Lead Product(s) : Red Blood Cell-Encapsulated Arginine Deiminase
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Eryaspase (GRASPA®), an L-asparaginase encapsulated inside donor-derived red blood cells, demonstrated sustained asparaginase enzyme activity above the threshold of >100 U/L at trough levels 14 days after first infusion in 92.5% of patients.
Product Name : Eryaspase
Product Type : Enzyme
Upfront Cash : Inapplicable
June 04, 2022
Lead Product(s) : Eryaspase
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Catalent Pharma Solutions
Deal Size : $44.5 million
Deal Type : Acquisition
Details : The deal includes an exclusive long-term supply agreement for Catalent to support Erytech’s lead product candidate eryaspase (GRASPA®), a red blood cell-derived product, which is currently in late-stage development for the treatment of acute lymphobla...
Product Name : Graspa
Product Type : Enzyme
Upfront Cash : Undisclosed
April 25, 2022
Lead Product(s) : Eryaspase
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Catalent Pharma Solutions
Deal Size : $44.5 million
Deal Type : Acquisition
Lead Product(s) : Undisclosed
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ERYTECH to Present Novel Vesiculation Approach at the 24th Meeting of the European Red Cell Society
Details : ERYCAPS, encapsulate active drug substances inside red blood cells using reversible hypotonic and hypertonic osmotic stress, uses transfusion-grade red blood cells taken from blood donors with a specific blood type, compatible with the blood type of pati...
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
April 04, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ERYTECH Requested a Pre-BLA Meeting with the FDA to Discuss Path to Approval in ALL
Details : Results from the NOPHO-sponsored Phase 2 clinical trial demonstrated that eryaspase in combination with chemotherapy, administered every two weeks, provides a sustained asparaginase enzyme activity level, and is generally well tolerated with few hypersen...
Product Name : Eryaspase
Product Type : Enzyme
Upfront Cash : Inapplicable
April 20, 2021
Lead Product(s) : L-Asparaginase,Gemcitabine
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ERYTECH Completes Enrollment in TRYbeCA-1 Phase 3 Trial in Second-Line Pancreatic Cancer
Details : TRYbeCA-1, the pivotal Phase 3 clinical trial evaluating eryaspase, in second-line metastatic pancreatic cancer, has completed patient enrollment. A total of 510 patients participated in the trial, slightly above the target enrollment of 482 patients.
Product Name : Eryaspase
Product Type : Enzyme
Upfront Cash : Inapplicable
December 14, 2020
Lead Product(s) : L-Asparaginase,Gemcitabine
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Primary finding of the NOR-GRASPALL-2016 trial suggest that eryaspase achieved the target level and duration of asparaginase activity in these patients.
Product Name : Eryaspase
Product Type : Enzyme
Upfront Cash : Inapplicable
September 06, 2020
Details : Oral presentation to discuss findings from the Nordic Society of Paediatric Haematology and Oncology (NOPHO)-sponsored Phase 2 trial that confirm the potential of eryaspase as a treatment option for ALL.
Product Name : Eryaspase
Product Type : Enzyme
Upfront Cash : Inapplicable
May 11, 2020