Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Anti Staphylococcus aureus Bacteriophage
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Recipient : Phaxiam Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Erytech and Pherecydes Announce Merger and Name Change to Phaxiam Therapeutics
Details : The new company will focus on developing innovative extended bacteriophage therapies to target antimicrobial resistance including, PhagoDAIR (anti S. aureus bacteriophage), world’s first study of phage therapy, for patients with knee or hip prosthetic ...
Brand Name : PhagoDAIR
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 26, 2023
Lead Product(s) : Anti Staphylococcus aureus Bacteriophage
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Recipient : Phaxiam Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Anti-Staphylococcus Aureus Bacteriophage
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Recipient : Pherecydes Pharma
Deal Size : Undisclosed
Deal Type : Merger
Details : Strategic combination will accelerate development of extended phage therapies for antimicrobial resistance including Anti-Staphylococcus aureus Bacteriophages, in particular via the phase II PhagoDAIR study conducted by PHERECYDES.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
February 15, 2023
Lead Product(s) : Anti-Staphylococcus Aureus Bacteriophage
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Recipient : Pherecydes Pharma
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Erythrocytes Encapsulating L-asparaginase
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ERYTECH Provides Regulatory Update
Details : In multiple clinical trials, Graspa (erythrocytes encapsulating L-asparaginase) showed promising results for patients, in hypersensitive acute lymphoblastic leukemia (ALL) to pegylated asparaginase therapy.
Brand Name : Graspa
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 24, 2022
Lead Product(s) : Erythrocytes Encapsulating L-asparaginase
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eryaspase
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Catalent Pharma Solutions
Deal Size : $44.5 million
Deal Type : Acquisition
Details : The deal includes an exclusive long-term supply agreement for Catalent to support Erytech’s lead product candidate eryaspase (GRASPA®), a red blood cell-derived product, which is currently in late-stage development for the treatment of acute lymphobla...
Brand Name : Graspa
Molecule Type : Large molecule
Upfront Cash : Undisclosed
April 25, 2022
Lead Product(s) : Eryaspase
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Catalent Pharma Solutions
Deal Size : $44.5 million
Deal Type : Acquisition
Details : Eryaspase (GRASPA®), an L-asparaginase encapsulated inside donor-derived red blood cells, demonstrated sustained asparaginase enzyme activity above the threshold of >100 U/L at trough levels 14 days after first infusion in 92.5% of patients.
Brand Name : Eryaspase
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 06, 2022
Lead Product(s) : RBC-loaded Enzyme
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ERYTECH to Present Novel Vesiculation Approach at the 24th Meeting of the European Red Cell Society
Details : ERYCAPS, encapsulate active drug substances inside red blood cells using reversible hypotonic and hypertonic osmotic stress, uses transfusion-grade red blood cells taken from blood donors with a specific blood type, compatible with the blood type of pati...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 04, 2022
Lead Product(s) : RBC-loaded Enzyme
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Red Blood Cell-encapsulated Arginine Deiminase
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ERYTECH Expands Patent Portfolio for the Treatment of Rare Metabolic Diseases
Details : US patent application for Enzyme replacement therapy cover arginine deiminase encapsulated into red blood cells for the treatment of arginase-1 deficiency (A1D), a debilitating rare metabolic disease.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 08, 2022
Lead Product(s) : Red Blood Cell-encapsulated Arginine Deiminase
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Peg L asparaginase
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ERYTECH Requested a Pre-BLA Meeting with the FDA to Discuss Path to Approval in ALL
Details : Results from the NOPHO-sponsored Phase 2 clinical trial demonstrated that eryaspase in combination with chemotherapy, administered every two weeks, provides a sustained asparaginase enzyme activity level, and is generally well tolerated with few hypersen...
Brand Name : Eryaspase
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 20, 2021
Lead Product(s) : Peg L asparaginase
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : L-asparaginase,Paclitaxel,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ERYTECH Completes Enrollment in TRYbeCA-1 Phase 3 Trial in Second-Line Pancreatic Cancer
Details : TRYbeCA-1, the pivotal Phase 3 clinical trial evaluating eryaspase, in second-line metastatic pancreatic cancer, has completed patient enrollment. A total of 510 patients participated in the trial, slightly above the target enrollment of 482 patients.
Brand Name : Eryaspase
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 14, 2020
Lead Product(s) : L-asparaginase,Paclitaxel,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Peg L asparaginase
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Oral presentation to discuss findings from the Nordic Society of Paediatric Haematology and Oncology (NOPHO)-sponsored Phase 2 trial that confirm the potential of eryaspase as a treatment option for ALL.
Brand Name : Eryaspase
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 05, 2020
Lead Product(s) : Peg L asparaginase
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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