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                            01

                            Abivax

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                            Lead Product(s) : Obefazimod,Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Abivax Presents Preclinical Data for UC Therapy with Obefazimod and Etrasimod

                            Details : Abivax is actively conducting preclinical studies ABX-464 (obefazimod) in combination with Etrasimod for treating Inflammatory Bowel Disease (IBD) in the Mouse Model.

                            Brand Name : ABX-464

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 25, 2024

                            Lead Product(s) : Obefazimod,Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Everest Medicines

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Everest Medicines Announces Acceptance of VELSIPITY® New Drug Application in Macau

                            Details : Velsipity (etrasimod) is an FDA-approved oral S1P receptor modulator, with its NDA accepted in Macau for adults with moderately to severely active ulcerative colitis.

                            Brand Name : Velsipity

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 10, 2024

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Everest Medicines

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Everest Medicines Announces Positive Topline Results from Induction Period of Etrasimod Phase 3 Clinical Trial...

                            Details : Velsipity (etrasimod) is a once-daily, oral, sphingosine 1-phosphate (S1P) receptor modulator that selectively binds with S1P receptor subtypes 1, 4, and 5. It is approved for the treatment of patients with moderately to severely active ulcerative coliti...

                            Brand Name : Velsipity

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 30, 2023

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Pfizer Inc

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            U.S. FDA Approves Pfizer’s VELSIPITY™ for Adults with Moderately to Severely Active Ulcerative Colitis (UC...

                            Details : Velsipity (etrasimod), an oral, once-daily, selective sphingosine-1-phosphate (S1P) receptor modulator, is approved by the FDA for adults with moderately to severely active ulcerative colitis (UC).

                            Brand Name : Velsipity

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 13, 2023

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

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                            05

                            Everest Medicines

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Everest Medicines Announces Completion of Patient Enrollment in Phase 3 Clinical Trial of Etrasimod in Asia

                            Details : APD334 (etrasimod) is an oral, once-a-day, selective sphingosine 1-phosphate (S1P) receptor modulator designed for optimized pharmacology and engagement of S1P receptors 1, 4, and 5. It is being investigated for the treatment of moderate-severe active ul...

                            Brand Name : APD334

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 17, 2023

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Pfizer Inc

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase III

                            Sponsor : Everest Medicines

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Everest Medicines' Licensing Partner Pfizer Announces FDA and EMA Acceptance of Etrasimod Regulatory Submissio...

                            Details : Etrasimod is an oral, once-a-day, selective sphingosine 1-phosphate (S1P) receptor modulator designed for optimized pharmacology and engagement of S1P receptors 1, 4, and 5. In addition to UC, it is being investigated for a range of other immuno-inflamma...

                            Brand Name : APD334

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 21, 2022

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase III

                            Sponsor : Everest Medicines

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Pfizer Inc

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Pfizer Presents ELEVATE Pivotal Findings Demonstrating Etrasimod’s Potentially Best-in-Class Profile in Ulce...

                            Details : APD334 (Etrasimod) is an oral, once-a-day, selective sphingosine 1-phosphate (S1P) receptor modulator designed for optimized pharmacology and engagement of S1P receptors 1, 4, and 5.

                            Brand Name : APD334

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 24, 2022

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Pfizer Announces Positive Top-line Results from Yearlong Phase 3 Trial of Etrasimod in Ulcerative Colitis, Und...

                            Details : Etrasimod is an oral, once-a-day, selective sphingosine 1-phosphate (S1P) receptor modulator designed for optimized pharmacology and engagement of S1P receptors 1, 4, and 5.

                            Brand Name : APD334

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 29, 2022

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Pfizer Inc

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Pfizer Announces Positive Top-Line Results for Phase 3 Trial of Etrasimod in Ulcerative Colitis Patients

                            Details : Etrasimod is an oral, once-a-day, selective sphingosine 1-phosphate (S1P) receptor modulator being investigated for a range of immuno-inflammatory diseases including ulcerative colitis, Crohn’s Disease, atopic dermatitis, eosinophilic esophagitis, and ...

                            Brand Name : APD334

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 23, 2022

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Arena

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                            Arena

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                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : $6,700.0 million

                            Deal Type : Acquisition

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                            Pfizer Completes Acquisition of Arena Pharmaceuticals

                            Details : Arena Pharmaceuticals brings to Pfizer a portfolio of diverse and promising development-stage therapeutic candidates in gastroenterology, dermatology, and cardiology, including etrasimod, an oral, selective sphingosine 1-phosphate (S1P) receptor modulato...

                            Brand Name : APD334

                            Molecule Type : Small molecule

                            Upfront Cash : $6,700.0 million

                            March 11, 2022

                            Lead Product(s) : Etrasimod

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : $6,700.0 million

                            Deal Type : Acquisition

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