Lead Product(s) : Quemliclustat,Zimberelimab,Etrumadenant
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Taiho Pharmaceutical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Taiho Exercises License Option for Quemliclustat in Japan and Asia
Details : Under the license agreement, Taiho will further support the development & commercialization of AB680 (quemliclustat) & will operationalize the PRISM-1 study in Japan as part of its mission.
Brand Name : AB680
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 08, 2024
Lead Product(s) : Quemliclustat,Zimberelimab,Etrumadenant
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Taiho Pharmaceutical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Etrumadenant,Zimberelimab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Arcus Biosciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Domvanalimab is an Fc-silent investigational monoclonal antibody that is designed to bind to TIGIT, a protein receptor on immune cells that acts as a brake on the immune response.
Brand Name : AB154
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 19, 2022
Lead Product(s) : Etrumadenant,Zimberelimab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Arcus Biosciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Etrumadenant,Zimberelimab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Arcus Bioscience
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Domvanalimab is an Fc-silent investigational monoclonal antibody that is designed to bind to TIGIT, a protein receptor on immune cells that acts as a brake on the immune response.
Brand Name : AB154
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 28, 2022
Lead Product(s) : Etrumadenant,Zimberelimab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Arcus Bioscience
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Domvanalimab,Zimberelimab,Etrumadenant
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Gilead Sciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ARC-7 and the ongoing ARC-10 Phase 3 registrational study will continue to enroll as planned, and preparations for additional Phase 3 studies are underway for domvanalimab-based combinations across various cancer types.
Brand Name : AB154
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 24, 2021
Lead Product(s) : Domvanalimab,Zimberelimab,Etrumadenant
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Gilead Sciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Eganelisib,Etrumadenant
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Arcus Biosciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Infinity to Present at New York Academy of Sciences’ Frontiers in Cancer Immunotherapy 2021
Details : The Phase 1b clinical trial is a global multi-center, open-label trial of CERC-007 that will enroll around 12 subjects with active adult onset Still’s disease with a primal goal of the study will be to determine the safety and tolerability of CERC-007 ...
Brand Name : IPI-549
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 05, 2021
Lead Product(s) : Eganelisib,Etrumadenant
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Arcus Biosciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Zimberelimab,Etrumadenant,AB154
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Gilead Sciences
Deal Size : $2,000.0 million
Deal Type : Collaboration
Details : Under this agreement, Gilead Gains Broad Access to Arcus’s Clinical and Preclinical Pipeline of Immuno-Oncology Product Candidates that Target Critical Biological Pathways. Arcus to continue to independently conduct research on New Targets.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : $175.0 million
May 27, 2020
Lead Product(s) : Zimberelimab,Etrumadenant,AB154
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Gilead Sciences
Deal Size : $2,000.0 million
Deal Type : Collaboration
Lead Product(s) : Zimberelimab,Etrumadenant,AB154
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Taiho Pharmaceutical
Deal Size : $275.0 million
Deal Type : Licensing Agreement
Details : Taiho’s in-licensing facilitates global development and commercialization of zimberelimab as a monotherapy and as a combination backbone for Arcus’s and Taiho’s oncology portfolios.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
February 26, 2020
Lead Product(s) : Zimberelimab,Etrumadenant,AB154
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Taiho Pharmaceutical
Deal Size : $275.0 million
Deal Type : Licensing Agreement
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