Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Dinutuximab
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Recordati
Deal Size : $847.0 million
Deal Type : Acquisition
Details : Recordati will expand its pipeline by acquiring EUSA Pharma pipeline and enhances the breadth of indications which include Qarziba®, an anti-GD2 monoclonal antibody, Sylvant®, an anti-IL-6 monoclonal antibody, Fotivda®, an oral highly selective small ...
Brand Name : Qarziba
Molecule Type : Large molecule
Upfront Cash : Undisclosed
December 03, 2021
Lead Product(s) : Dinutuximab
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Recordati
Deal Size : $847.0 million
Deal Type : Acquisition
Lead Product(s) : Siltuximab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : This pivotal study will evaluate the efficacy and safety of standard of care (SOC) with or without intravenous siltuximab in selected hospitalised patients with COVID-19 previously treated with corticosteroids or another respiratory virus infection.
Brand Name : Sylvant
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 17, 2020
Lead Product(s) : Siltuximab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Dinutuximab
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : BeiGene
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : QARZIBA® is a monoclonal antibody that is specifically directed against the carbohydrate moiety of disialoganglioside 2 (GD2), which is overexpressed on neuroblastoma cells.
Brand Name : Qarziba
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 09, 2020
Lead Product(s) : Dinutuximab
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : BeiGene
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tivozanib,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Aveo Oncology
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The Phase 2 portion of the study was designed to assess the safety, tolerability, and anti-tumor activity of the full dose and schedule of PO tivozanib, in combination with IV nivolumab.
Brand Name : Fotivda
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 05, 2020
Lead Product(s) : Tivozanib,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Aveo Oncology
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Siltuximab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Siltuximab is a monoclonal antibody that directly neutralizes interleukin (IL)-6, an inflammatory cytokine detected at elevated levels in multiple inflammatory conditions, including COVID-19. It specifically binds to IL-6, thereby inactivating IL-6 induc...
Brand Name : Sylvant
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 02, 2020
Lead Product(s) : Siltuximab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Siltuximab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A third of patients with COVID-19 taking EUSA Pharma's interleukin (IL)-6 targeted monoclonal antibody siltuximab have experienced a clinical improvement, reveals a case-control trial in Italy.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 01, 2020
Lead Product(s) : Siltuximab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Siltuximab
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The step was followed by the release of initial data from China suggesting a role of IL-6 in the development of Acute Respiratory Distress Syndrome as a result of COVID-19.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 18, 2020
Lead Product(s) : Siltuximab
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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