Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evecxia Completes Pre-IND Meeting with FDA for EVX-101 in Depression
Details : EVX-101 is a novel, proprietary gastro-retentive, sustained-release tablet formulation of 5-HTP, the natural precursor to serotonin. It is under trials for the treatment of major depressive disorder.
Brand Name : EVX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 25, 2024
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evecxia Therapeutics Reports No Toxicology Findings in Nonclinical GLP Studies of Adjunctive EVX-101
Details : EVX-101 is a novel, proprietary, gastro-retentive, sustained-release tablet formulation of 5-hydroxytryptophan (5-HTP), which is investigated for the treatment of major depressive disorder.
Brand Name : EVX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 02, 2023
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Quotient Sciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EVX-101 is a novel, proprietary, gastro-retentive, sustained-release tablet formulation of 5-hydroxytryptophan (5-HTP), which is investigated for the treatment of major depressive disorder.
Brand Name : EVX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 21, 2023
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Quotient Sciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EVX-101 is a proprietary, oral tablet, gastroretentive, slow-release formulation of 5-HTP and low-dose carbidopa. It is being developed for patients with depression responding inadequately to first-line SSRI/SNRI antidepressants monotherapy.
Brand Name : EVX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 28, 2023
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EVX-101 is a novel, proprietary gastro-retentive, sustained-release tablet formulation of 5-hydroxytryptophan (5-HTP), the natural precursor to serotonin, and low-dose carbidopa. It is being investegated for major depressive disorder.
Brand Name : EVX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 10, 2023
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evecxia Therapeutics Reports Favorable Data from a Phase 1 SAD/MAD Trial
Details : EVX-101 is a novel, proprietary gastro-retentive, sustained-release tablet formulation of 5-hydroxytryptophan (5-HTP), the natural precursor to serotonin. It is under phase 1 clinical trials for the treatment of major depressive disorder.
Brand Name : EVX-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 10, 2023
Lead Product(s) : HSDB 4295,Carbidopa
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : EVX-301
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EVX-301 (5-hydroxytryptophan) is designed to quickly and optimally amplify brain extracellular serotonin and hence serotonin neurotransmission, as a rescue therapy for patients hospitalized for acute suicidal ideation crisis.
Brand Name : EVX-301
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 15, 2023
Lead Product(s) : EVX-301
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : EVX-101
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EVX-101 is a clinical-stage drug candidate currently being developed as an adjunctive treatment for when first-line antidepressants alone are inadequate.
Brand Name : EVX-101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 24, 2022
Lead Product(s) : EVX-101
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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