[{"orgOrder":0,"company":"Evergreen Theragnostics","sponsor":"Precirix","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2021","type":"Partnership","leadProduct":"131-I Conjugated Anti-HER2 sdAb 2Rs15d","moa":"HER2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Evergreen Theragnostics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Evergreen Theragnostics \/ Precirix","highestDevelopmentStatusID":"7","companyTruncated":"Evergreen Theragnostics \/ Precirix"},{"orgOrder":0,"company":"Evergreen Theragnostics","sponsor":"Cellectar","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2021","type":"Agreement","leadProduct":"131-I Iopofosine","moa":"DNA cross-linking","graph1":"Oncology","graph2":"Phase II","graph3":"Evergreen Theragnostics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Evergreen Theragnostics \/ Cellectar","highestDevelopmentStatusID":"8","companyTruncated":"Evergreen Theragnostics \/ Cellectar"},{"orgOrder":0,"company":"Evergreen Theragnostics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"68-Ga EVG321","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Evergreen Theragnostics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Evergreen Theragnostics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Evergreen Theragnostics \/ Inapplicable"},{"orgOrder":0,"company":"Evergreen Theragnostics","sponsor":"Lantheus Holding","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2025","type":"Acquisition","leadProduct":"177-Lu EVG-321","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Evergreen Theragnostics","amount2":1,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":1,"dosageForm":"Undisclosed","sponsorNew":"Evergreen Theragnostics \/ Lantheus Holding","highestDevelopmentStatusID":"4","companyTruncated":"Evergreen Theragnostics \/ Lantheus Holding"},{"orgOrder":0,"company":"Evergreen Theragnostics","sponsor":"Medical University of Innsbruck","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2024","type":"Collaboration","leadProduct":"177-Lu EVG-321","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Evergreen Theragnostics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Evergreen Theragnostics \/ Medical University of Innsbruck","highestDevelopmentStatusID":"4","companyTruncated":"Evergreen Theragnostics \/ Medical University of Innsbruck"},{"orgOrder":0,"company":"Evergreen Theragnostics","sponsor":"Petrichor Healthcare","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Radiolabelled Compounds","year":"2024","type":"Financing","leadProduct":"177-Lu EVG-321","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Evergreen Theragnostics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Evergreen Theragnostics \/ Petrichor Healthcare","highestDevelopmentStatusID":"4","companyTruncated":"Evergreen Theragnostics \/ Petrichor Healthcare"}]

Find Clinical Drug Pipeline Developments & Deals by Evergreen Theragnostics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Through the acquisition, Lantheus will leverage Evergreen radiolabelled product pipeline, which includes EVG-321 (177Lu-EVG-321), is being evaluated for small cell lung cancer.

                          Product Name : EVG-321

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : $250.0 million

                          January 28, 2025

                          Lead Product(s) : 177-Lu EVG-321

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Lantheus Holding

                          Deal Size : $1,002.5 million

                          Deal Type : Acquisition

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                          02

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : 68Ga-EVG321 is being evaluating in the early-stage clinical trials studies for the treatment of patients with small cell lung cancer in the European Union.

                          Product Name : 68-Ga EVG321

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 18, 2024

                          Lead Product(s) : 68-Ga EVG321

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : The collaboration aims to advance the clinical development of EVG-321 (177Lu-EVG-321), which is being evaluated in the early-stage clinical trial studies for the treatment of small cell lung cancer.

                          Product Name : EVG-321

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Undisclosed

                          May 21, 2024

                          Lead Product(s) : 177-Lu EVG-321

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Medical University of Innsbruck

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Evergreen's financing supports clinical trials for its theragnostic pair, 177Lu-EVG-321 and 68Ga-EVG-321, aimed at small cell lung cancer treatment.

                          Product Name : EVG-321

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Undisclosed

                          April 16, 2024

                          Lead Product(s) : 177-Lu EVG-321

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Petrichor Healthcare

                          Deal Size : $26.0 million

                          Deal Type : Financing

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                          05

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : The agreement with Evergreen provides long term commercial supply of iopofosine I-131 and supply of clinical study material for Cellectar’s pivotal study in Waldenstrom’s macroglobulinemia (WM) as well as ongoing Phase 1 and Phase 2 clinical studies.

                          Product Name : CLR-131

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Undisclosed

                          August 16, 2021

                          Lead Product(s) : 131-I Iopofosine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Cellectar

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          06

                          MAGHREB PHARMA
                          Not Confirmed
                          MAGHREB PHARMA
                          Not Confirmed

                          Details : Under the terms of the deal, Evergreen will provide US-based manufacturing for Precirix’s lead product candidate, CAM-H2. CAM-H2 is being evaluated in a Phase I/II clinical trial targeting HER2-positive metastatic breast and gastric cancer.

                          Product Name : Undisclosed

                          Product Type : Radiolabelled Compounds

                          Upfront Cash : Undisclosed

                          April 28, 2021

                          Lead Product(s) : 131-I Conjugated Anti-HER2 sdAb 2Rs15d

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Precirix

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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