Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Everolimus
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Breckenridge Gains FDA Nod for Everolimus, Afinitor Disperz Generic
Details : Afinitor Disperz (everolimus) is an mTOR inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of tuberous sclerosis complex.
Product Name : Afinitor Disperz-Generic
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 29, 2025
Lead Product(s) : Everolimus
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Everolimus
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Natco Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Everolimus 10mg (Afinitor) Launched
Details : Everolimus is the generic name for the trade name drug Afinitor. Breckenridge has launched 10mg strength of Everolimus Tablets used as an immunosuppressant to prevent rejection of organ transplants and in the treatment of renal cell cancer and other tumo...
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
October 01, 2021
Lead Product(s) : Everolimus
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Natco Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Everolimus
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Breckenridge Announces Final Approval of its ANDA for Everolimus Tablets (generic for Zortress®)
Details : Zortress-Generic (everolimus) inhibits antigenic and interleukin (IL-2 and IL-15) stimulated activation and proliferation of T and B lymphocytes. It is indicated for the prophylaxis of organ rejection in adult patients.
Product Name : Zortress-Generic
Product Type : Small molecule
Upfront Cash : Not Applicable
June 01, 2021
Lead Product(s) : Everolimus
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Everolimus
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Natco Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Breckenridge Announces Final Approval of its ANDA for Everolimus Tablets (Generic for Afinitor®)
Details : Breckenridge plans to launch Everolimus Tablets in 2.5mg, 5mg and 7.5mg strengths during the second quarter of 2021 in a blister card packaging configuration.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
March 08, 2021
Lead Product(s) : Everolimus
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Natco Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Everolimus
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Upsher-Smith Expands Rare Disease Portfolio with Launch of Torpenz™ (everolimus) Tablets
Details : Torpenz (everolimus) inhibits antigenic and interleukin (IL-2/15) stimulated activation and proliferation of T and B lymphocytes. It is indicated for Tuberous Sclerosis Complex.
Product Name : Torpenz
Product Type : Small molecule
Upfront Cash : Not Applicable
August 05, 2024
Lead Product(s) : Everolimus
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Everolimus
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Abbott's Breakthrough Dissolving Stent Receives FDA Approval for Arteries below the Knee
Details : The FDA approved the Esprit™ BTK Everolimus Eluting Resorbable Scaffold System to keep arteries open, delivering Everolimus to support healing in patients with chronic limb-threatening ischemia.
Product Name : Esprit
Product Type : Small molecule
Upfront Cash : Not Applicable
April 29, 2024
Lead Product(s) : Everolimus
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Everolimus
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Eris Lifesciences
Deal Size : $43.8 million
Deal Type : Divestment
Biocon Biologics Announces Divestment of Two Non-Core Branded Formulations
Details : Through the divestment, Eris gains Biocon's Dermatology and Nephrology branded formulations business units in India that mostly comprised of its legacy small molecules’ brands, including Advacan (everolimus), an anti-cancer medicine.
Product Name : Advacan
Product Type : Small molecule
Upfront Cash : Undisclosed
November 09, 2023
Lead Product(s) : Everolimus
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Eris Lifesciences
Deal Size : $43.8 million
Deal Type : Divestment
Lead Product(s) : n.c.a. 177Lu-Edotreotide,Everolimus
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Temasek
Deal Size : $272.7 million
Deal Type : Financing
Details : The net financing will support the development of ITM’s broad Targeted Radionuclide Therapies oncology pipeline and enhance phase III clinical development for its lead pipeline candidate, ITM-11 (n.c.a. 177Lu-edotreotide) in gastroenteropancreatic neur...
Product Name : ITM-11
Product Type : Peptide
Upfront Cash : Undisclosed
June 05, 2023
Lead Product(s) : n.c.a. 177Lu-Edotreotide,Everolimus
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Temasek
Deal Size : $272.7 million
Deal Type : Financing
Lead Product(s) : Everolimus
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Biocon Expands its Generic Formulations Portfolio with the Launch of Everolimus Tablets in the US
Details : Everolimus tablets, a generic version of Afinitor® have been introduced in four strengths of 2.5mg, 5mg, 7.5mg and 10mg, with the 10 mg tablet used to treat certain types of cancers and tumours.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
October 04, 2021
Lead Product(s) : Everolimus
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Xentuzumab,Everolimus,Exemestane
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Undisclosed
Deal Type : Agreement
Aragen Announces Expansion of Research Agreement with Boehringer Ingelheim
Details : Xentuzumab* (BI 836845) is a humanized immunoglobulin G (IgG) 1 monoclonal antibody (mAb) that targets insulin-like growth factor (IGF) ligands IGF-1 and IGF-2 for treatment of breast cancer.
Product Name : BI 836845
Product Type : Large molecule
Upfront Cash : Undisclosed
June 29, 2021
Lead Product(s) : Xentuzumab,Everolimus,Exemestane
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Undisclosed
Deal Type : Agreement