Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Botulinum toxin type A
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evolus Launches Nuceiva in Spain for Botulinum Toxin Type A
Details : Nuceiva (prabotulinumtoxinA) is an acetylcholine release inhibitor and a neuromuscular blocking agent indicated for the temporary improvement in the appearance of moderate to severe glabellar lines.
Brand Name : Nuceiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 12, 2024
Lead Product(s) : Botulinum toxin type A
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PrabotulinumtoxinA-xvfs
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Leerink Partners
Deal Size : $50.0 million
Deal Type : Public Offering
Evolus Announces Pricing of $50.0 Million Underwritten Offering of Common Stock
Details : Proceeds will support the commercialization of Jeuveau (prabotulinumtoxinA-xvfs), an ACH release inhibitor for improving glabellar lines.
Brand Name : Jeuveau
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 11, 2024
Lead Product(s) : PrabotulinumtoxinA-xvfs
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Leerink Partners
Deal Size : $50.0 million
Deal Type : Public Offering
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evolus Initiates Nuceiva® Launch in Germany and Austria
Details : Nuceiva (prabotulinumtoxinA) blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the successful docking and release of acetylcholine thereby leading to denervation of the muscle an...
Brand Name : Nuceiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 27, 2023
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PrabotulinumtoxinA-xvfs
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Jeuveau (prabotulinumtoxinA) blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the successful docking and release of acetylcholine thereby leading to denervation of the muscle an...
Brand Name : Jeuveau
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 28, 2023
Lead Product(s) : PrabotulinumtoxinA-xvfs
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evolus Receives Regulatory Approval for Nuceiva® in Australia
Details : Nuceiva (prabotulinumtoxinA) blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the successful docking and release of acetylcholine thereby leading to denervation of the muscle an...
Brand Name : Nuceiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 23, 2023
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Jeuveau (prabotulinumtoxinA) blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the successful docking and release of acetylcholine thereby leading to denervation of the muscle an...
Brand Name : Jeuveau
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 23, 2023
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Evolus Broadens Its International Presence with Nuceiva® Launch in Great Britain
Details : Nuceiva® (botulinum toxin type A) is approved for temporary improvement in the appearance of moderate to severe vertical lines between eyebrows seen at maximum frown, when severity of facial lines has an important psychological impact in adults below 65...
Brand Name : Nuceiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 04, 2022
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PrabotulinumtoxinA-Xvfs
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Newly Published Post Hoc Analysis Evaluates Efficacy of Jeuveau® in Adult Males Compared to BOTOX®
Details : Peer-reviewed, post hoc analysis published in Aesthetic Surgery Journal showed with high consistency that males treated with Jeuveau® (prabotulinumtoxinA-xvfs), neurotoxin product, had higher responder rates than those treated with BOTOX across nearly a...
Brand Name : Jeuveau
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 24, 2022
Lead Product(s) : PrabotulinumtoxinA-Xvfs
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Jeuveau (prabotulinumtoxinA) is approved for the temporary improvement in the appearance of moderate to severe vertical lines between the eyebrows seen at maximum frown (glabellar lines) in adults below 65 years of age.
Brand Name : Jeuveau
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 12, 2022
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The data showed Jeuveau® (prabotulinumtoxinA-xvfs) was well tolerated in both millennial and non-millennial patient populations, and highly effective for millennials with moderate-to-severe glabellar lines.
Brand Name : Jeuveau
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 02, 2022
Lead Product(s) : PrabotulinumtoxinA
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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