Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : EVO301
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Evommune Starts Phase 2 Trial of IL-18 Fusion Protein EVO301 for Atopic Dermatitis
Details : EVO301 is a serum albumin Fab-associated IL-18BP fusion protein, which is currently being evaluated for the treatment of adult patients with moderate-to-severe atopic dermatitis.
Product Name : EVO301
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
March 17, 2025
Lead Product(s) : EVO301
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : EVO756
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Evommune Announces Positive Results for MRGPRX2 Antagonist EVO756
Details : EVO756 is a potent, highly selective small molecule antagonist of mas-related G-protein coupled receptor X2 (MRGPRX2). It is being evaluated for the treatment of chronic spontaneous urticaria.
Product Name : EVO756
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 16, 2024
Lead Product(s) : EVO756
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : EVO756
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Evommune Starts Phase 2 Trial of EVO756 for Chronic Inducible Urticaria
Details : EVO756 is a potent, highly selective small molecule antagonist of MRGPRX2. It is being investigated for the treatment of chronic inducible urticaria.
Product Name : EVO756
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 09, 2024
Lead Product(s) : EVO756
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : EVO756
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Evommune Starts Phase 1 Trial for MRGPRX2 Antagonist in Urticaria
Details : EVO756 is a potent, highly selective small molecule antagonist of mas-related G-protein coupled receptor X2 (MRGPRX2). It is under phase 1 clinical development for chronic spontaneous urticaria.
Product Name : EVO756
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 18, 2024
Lead Product(s) : EVO756
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : EVO756
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Maruho
Deal Size : $60.0 million
Deal Type : Collaboration
Details : The collaboration aims to develop and commercialize EVO756 in Japan. Evommune’s MRGPRX2 antagonist, is an investigational therapy with the potential to be a first-in-class oral treatment for a variety of mast cell mediated disease.
Product Name : EVO756
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 27, 2023
Lead Product(s) : EVO756
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Maruho
Deal Size : $60.0 million
Deal Type : Collaboration
Lead Product(s) : EVO101
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Evommune Initiates Phase 2a Proof-of-Concept Clinical Trial to Evaluate EVO101 in Atopic Dermatitis
Details : In the Phase 2a study, AD patients will apply EVO101 cream twice daily for eight weeks. Primary efficacy will be assessed by changes from baseline in the Eczema Area and Severity Index (EASI).
Product Name : EVO101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 28, 2022
Lead Product(s) : EVO101
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : EVO101
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : EVO101 is a novel small molecule inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) which broadly inhibits innate inflammation and is being developed as a treatment for inflammatory skin diseases.
Product Name : EVO101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 21, 2022
Lead Product(s) : EVO101
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Dermatology
Study Phase : Discovery
Sponsor : Andera Partners
Deal Size : $83.0 million
Deal Type : Series A Financing
Details : The financing will allow to advance four programs of Evommune in pipeline among which three of the compounds include IRAK4/TrkA, broadly inhibits innate inflammation; RORγt, treating inflammation; MRGPRX2, to treat chronic pruritus and fourth compound i...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 09, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Dermatology
Highest Development Status : Discovery
Sponsor : Andera Partners
Deal Size : $83.0 million
Deal Type : Series A Financing