Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Icahn School of Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims to work on developing exosome-encapsulated AAV (exoAAV) vectors as a novel gene delivery technology aimed at improving treatments for heart disease.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
April 08, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Icahn School of Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Antibody-loaded exosomes, which covered recent advances on engineering exosomes as a display platform for biologics, new in vivo data on antibody-directed targeting of exosomes to tumours, and new data supporting the concept of in situ produced drug-load...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 05, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The nine presentations highlight the progress the Company has made in modulating exosome pharmacokinetics through extension of circulation half-life and improved tissue-targeting via display of ligands on Antibody-loaded Exosomes.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 25, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HSDB 4295
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Preclinical
Sponsor : Redmile Group
Deal Size : $95.4 million
Deal Type : Series C Financing
Evox Therapeutics Completes £69.2 Million Series C Financing
Details : Proceeds from this financing will support the advancement of Evox’s exosome-based therapeutics pipeline, including progression of several rare disease assets into the clinic, and continued development of its world-leading DeliverEX exosome drug platfor...
Product Name : EVX-101
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 18, 2021
Lead Product(s) : HSDB 4295
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Preclinical
Sponsor : Redmile Group
Deal Size : $95.4 million
Deal Type : Series C Financing
Details : During this research collaboration and five-target license agreement, Evox will be responsible for exosome engineering in order to achieve brain/CNS-targeting, drug loading and analytics and some in vitro and in vivo studies.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : $20.0 million
September 06, 2020
Details : The recently issued US patent provides broad coverage for pharmaceutical compositions comprising exosomes containing nucleic acid-based therapeutics, such as RNAi agents and antisense oligonucleotides, which have been loaded by electroporation.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
July 15, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Preclinical
Sponsor : Takeda Pharmaceutical
Deal Size : $882.0 million
Deal Type : Collaboration
Evox Therapeutics and Takeda Sign Multi-target Rare Disease Collaboration
Details : Deal allows Evox to continue advancing its exosome-based targeting and delivery technology, while also leveraging Takeda’s development and clinical expertise to advance these partnered programmes.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : $44.0 million
March 26, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Preclinical
Sponsor : Takeda Pharmaceutical
Deal Size : $882.0 million
Deal Type : Collaboration