Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : EXE-346
Therapeutic Area : Gastroenterology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ExeGi Pharma Announces First Patient Enrollment in the PROF Trial of EXE-346
Details : ExeGi investigational product candidate EXE-346, which is a microbiome modulator probiotic. Currently, it is being evaluated in the Phase I/II clinical trial studies for the treatment of excessive stool frequency in patients with an ileal pouch-anal anas...
Brand Name : EXE-346
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 08, 2023
Lead Product(s) : EXE-346
Therapeutic Area : Gastroenterology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : EXE-346
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : EXE-346 is a live biotherapeutic product (LBP) a blend of probiotic bacteria formulated in extremely high potency. The product is currently under development to manage excessive stool frequency in patients who have undergone an ileal pouch-anal anastomos...
Brand Name : EXE-346
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 26, 2023
Lead Product(s) : EXE-346
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : EXE-346
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ExeGi Pharma Announces FDA Orphan Drug Designation for EXE-346 Live Biotherapeutic
Details : EXE-346 is an LBP which contains a fixed-proportion of 8 strains of live probiotic bacteria which are intended for oral administration. EXE-346 is intended to decrease this inflammation of the pouch and prevent active disease flare-ups.
Brand Name : EXE-346
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 12, 2020
Lead Product(s) : EXE-346
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Live Biotherapeutic Product,Hydroxychloroquine Sulphate,Antibiotics
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Italian clinical study finds combined strains of live bacteria reduced diarrhea and lessened progression of symptoms in hospitalized COVID-19 patients.
Brand Name : SivoBiome
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 13, 2020
Lead Product(s) : Live Biotherapeutic Product,Hydroxychloroquine Sulphate,Antibiotics
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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