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                            01

                            Fate Therapeutics

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                            Lead Product(s) : FT819,Fludarabine Phosphate,Cyclophosphamide

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Fate Therapeutics Treats First Lupus Patient in Phase 1 Study of FT819 CAR T-Cell Program

                            Details : FT819 is the first-ever, off-the-shelf, iPSC-derived CAR T-cell therapy, which is currently being evaluated for the treatment of moderate to severe active systemic lupus erythematosus.

                            Brand Name : FT819

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            May 09, 2024

                            Lead Product(s) : FT819,Fludarabine Phosphate,Cyclophosphamide

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Fate Therapeutics

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                            Lead Product(s) : FT522,Rituximab,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Fate Presents FT522 Preclinical Data for Autoimmune Diseases At ASGCT

                            Details : FT522 is an iPSC-derived CAR NK cell targeting CD19 with ADR technology, under evaluation for relapsed/refractory B-cell lymphoma.

                            Brand Name : FT522

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            May 03, 2024

                            Lead Product(s) : FT522,Rituximab,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Fate Therapeutics

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                            Lead Product(s) : FT576

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Fate Therapeutics Prices $100 Million Underwritten Offering and Private Placement

                            Details : The Company plans to use net proceeds to fund clinical trials and nonclinical studies of its candidates, including FT576, an investigational CAR NK cell cancer immunotherapy.

                            Brand Name : FT576

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            March 19, 2024

                            Lead Product(s) : FT576

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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                            04

                            Fate Therapeutics

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                            Fate Therapeutics

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                            Lead Product(s) : FT825

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Fate Therapeutics Initiates Phase 1 Trial for FT825 / ONO-8250 in Advanced Solid Tumors

                            Details : ONO-8250 (FT825) is a multiplexed-engineered CAR T-cell candidate targeting HER2, under Phase 1 trials for HER2-expressing advanced solid tumors.

                            Brand Name : ONO-8250

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 08, 2024

                            Lead Product(s) : FT825

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Fate Therapeutics

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                            Lead Product(s) : Allogenic CAR NK Cell,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Janssen

                            Deal Size : $3,100.0 million

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            Fate Therapeutics Announces Termination of Collaboration Agreement with Janssen, Pipeline Prioritization, Next...

                            Details : FT576 (CAR NK cells) is an investigational, universal, off-the-shelf NK cell cancer immunotherapy derived from a clonal master iPSC line. FT576 incorporates a proprietary CAR that targets BCMA, a novel high-affinity 158V and non-cleavable CD16 (hnCD16) F...

                            Brand Name : FT576

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : $100.0 million

                            January 05, 2023

                            Lead Product(s) : Allogenic CAR NK Cell,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Janssen

                            Deal Size : $3,100.0 million

                            Deal Type : Termination

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                            06

                            Fate Therapeutics

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                            Lead Product(s) : FT819,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Fate Therapeutics Announces Clinical Safety and Activity Data of First-ever iPSC-derived CAR T-cell Therapy at...

                            Details : FT819 is an investigational, universal, off-the-shelf, T-cell receptor (TCR)-less CD19 chimeric antigen receptor (CAR) T-cell cancer immunotherapy derived from a clonal master induced pluripotent stem cell (iPSC) line.

                            Brand Name : FT819

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            December 10, 2022

                            Lead Product(s) : FT819,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Fate Therapeutics

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                            Lead Product(s) : ONO-8250

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Ono Pharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Fate Therapeutics Announces Exercise by ONO Pharmaceutical of Option to HER2-targeted CAR T-Cell Product Candi...

                            Details : Under the terms of the Collaboration and Option Agreement, the parties will jointly develop and commercialize FT825 (ONO-8250) in the U.S. and Europe, and ONO maintains exclusive development and commercialization rights for FT825 (ONO-8250) in the rest o...

                            Brand Name : FT825

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            November 07, 2022

                            Lead Product(s) : ONO-8250

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Ono Pharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Fate Therapeutics

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                            Lead Product(s) : FT819

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Fate Therapeutics to Present Clinical and Preclinical Data for iPSC Product Platform at the 2022 ASH Annual Me...

                            Details : FT819, an off-the-shelf CAR T-cell cancer immunotherapy derived from a clonal engineered master iPSC line with a novel 1XX CAR targeting CD19 inserted into the T-cell receptor alpha constant (TRAC) locus and edited for elimination of T-cell receptor (TCR...

                            Brand Name : FT819

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            November 03, 2022

                            Lead Product(s) : FT819

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Fate Therapeutics

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                            Lead Product(s) : GTB-3650,CAR NK Cell Therapy

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : GT Biopharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            GT Biopharma to Present New Data on Novel Dual-Antigen Targeting Approach Against AML at Upcoming 2022 ASH Ann...

                            Details : Preclinical data to be presented demonstrate that iPSC-derived, MICA/B-targeted CAR NK cells induced potent activity against AML cell line HL60, and further enhancement of activity was achieved in combination with GTB-3650 through antibody-dependent cell...

                            Brand Name : GTB-3650

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 03, 2022

                            Lead Product(s) : GTB-3650,CAR NK Cell Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : GT Biopharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Fate Therapeutics

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                            Lead Product(s) : FT536,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Fate Therapeutics to Present Clinical and Preclinical Data for iPSC Product Platform at the Society for Immuno...

                            Details : FT536 is an investigational, universal, off-the-shelf NK cell cancer immunotherapy derived from a clonal master engineered iPSC line. FT536 incorporates a proprietary CAR that targets the α3 domain of MICA and MICB.

                            Brand Name : FT536

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 05, 2022

                            Lead Product(s) : FT536,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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