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                          German Wound Congress
                          Not Confirmed

                          Details : Hyundai Bio and DNDi will aim to jointly conduct clinical research & development, and global deployment of a Xafty (niclosamide)-based dengue antiviral treatment.

                          Product Name : Xafty

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 06, 2025

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : DNDi

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Xafty's active ingredient, niclosamide's mechanism is to remove viruses by activating cell autophagy, it is being investigated for COVID-19 as an antiviral drug candidate.

                          Product Name : Xafty

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 28, 2024

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Niclosamide is an anthelmintic, small molecule drug candidate, that acts as a DNA inhibitor. It is currently being evaluated for the treatment of Dengue fever.

                          Product Name : Xafty

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 25, 2024

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Niclosamide is an anthelmintic, small molecule drug candidate, that acts as a DNA inhibitor. It is currently being evaluated for the treatment of Dengue fever.

                          Product Name : Xafty

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 25, 2024

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Through the agreement, the company will prioritize the clinical development of FW-UP (niclosamide), currently undergoing Phase I/II clinical trial studies for the treatment of ulcerative colitis.

                          Product Name : FW-UP

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 27, 2023

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          06

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Xafty is a novel broad-spectrum antiviral with niclosamide's mechanism that eliminates viruses that infiltrated cells and can solve RNA virus infections, capable of treating both COVID-19 and Dengue fever or Dengue virus infection.

                          Product Name : Xafty

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 13, 2023

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Xafty's active ingredient, niclosamide's mechanism is to remove viruses by activating cell autophagy, it is being investigated for COVID-19 as an antiviral drug candidate.

                          Product Name : Xafty

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 05, 2023

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Niclosamide is an antiviral, that shows potent activity against SARS-CoV-2. Niclosamide targets human cell pathways and the host’s ability to control viral replication as its MOA and is therefore resistant to mutation of the SARS-CoV-2 spike protein.

                          Product Name : UNI911

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 10, 2022

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Niclosamide, is a Potent Inhibitor of SARS-CoV-2 with Activity Against Multiple Variants for the treatment of COVID-2019 infections, was recently shown to exhibit potent antiviral activity against SARS-CoV-2.

                          Product Name : UNI911

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 22, 2022

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Company believes that FW-COV (Niclosamide). Part 2 of RESERVOIR Trial has the potential to contribute to global need for new therapies against SARS2 based on the positive safety data observed with earlier published in vitro COVID efficacy data. Topline D...

                          Product Name : FW-COV

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 01, 2022

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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