[{"orgOrder":0,"company":"Rebiotix","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Rbx2660","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Rebiotix","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Enema","sponsorNew":"Rebiotix \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Rebiotix \/ Not Applicable"},{"orgOrder":0,"company":"Rebiotix","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Rbx2660","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase 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\/ Not Applicable"},{"orgOrder":0,"company":"Ferring Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Rbx2660","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Ferring Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Enema","sponsorNew":"Ferring Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Ferring Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Ferring Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"Nadofaragene 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Pharmaceuticals","highestDevelopmentStatusID":"12","companyTruncated":"Ferring Pharmaceuticals \/ Ferring Pharmaceuticals"}]

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                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The agreement aims to scale manufacturing for Adstiladrin (nadofaragene firadenovec), an intravesical non-replicating gene therapy approved for BCG-unresponsive non-muscle invasive bladder cancer.

                          Brand Name : Adstiladrin

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 18, 2024

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Recipient : SK Pharmteco

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Adstiladrin (nadofaragene firadenovec) is the first FDA-approved intravesical gene therapy for high-risk BCG-unresponsive NMIBC with carcinoma in situ, evaluated for adult patients.

                          Brand Name : Adstiladrin

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          April 16, 2024

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Adstiladrin (nadofaragene firadenovec-vncg) is an FDA-approved gene therapy delivering a human IFNα2b gene to the bladder for treating BCG-unresponsive non-muscle invasive bladder cancer.

                          Brand Name : Adstiladrin

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          January 24, 2024

                          Lead Product(s) : Nadofaragene Firadenovec-vncg

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase IV

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the collaboration, Ferring will get exclusive rights to develop, manufacture and commercialise next generation microbiome-based therapeutics within the field of gastroenterology arising out of the collaboration.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          December 11, 2023

                          Lead Product(s) : Microbiome-based Therapy

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Discovery

                          Recipient : PharmaBiome

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : ADSTILADRIN® (nadofaragene firadenovec-vncg) is the first and only FDA-approved intravesical gene therapy for the treatment of adult patients with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer.

                          Brand Name : Adstiladrin

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 12, 2023

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the agreement, Royalty Pharma is acquiring a 5.1 percentage royalty on net sales of Adstiladrin (nadofaragene firadenovec-vncg), a gene therapy developed as a treatment for adult patients with BCG-unresponsive NMIBC, in the United States.

                          Brand Name : Adstiladrin

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : $300.0 million

                          August 23, 2023

                          Lead Product(s) : Nadofaragene Firadenovec-vncg

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Royalty Pharma

                          Deal Size : $500.0 million

                          Deal Type : Agreement

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Adstiladrin (nadofaragene firadenovec-vncg) is the first and only FDA-approved non-replicating adenovirus vector-based therapy for the treatment of adult patients with high-risk BCG-unresponsive NMIBC with carcinoma in situ (CIS) with or without papillar...

                          Brand Name : Adstiladrin

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 12, 2023

                          Lead Product(s) : Nadofaragene Firadenovec-vncg

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : SI-6603 (condoliase), which contains Condoliase as its active pharmaceutical ingredient, is intended to treat lumbar disc herniation via a single, direct intradiscal injection.

                          Brand Name : SI-6603

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 26, 2023

                          Lead Product(s) : Condoliase

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Rekovelle (follitropin delta) is a follicle-stimulating hormone made from recombinant human DNA that is used to promote follicular development in females with ovarian failure, reproduction and fertility.

                          Brand Name : Rekovelle

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 14, 2023

                          Lead Product(s) : Follitropin Delta

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Phase IV

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Rebyota (live fecal microbiota-jslm) is the first and only microbiome-based treatment approved by the U.S. FDA to prevent recurrence of Clostridioides difficile (C. diff) infection in individuals 18 years of age and older.

                          Brand Name : Rebyota

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 14, 2023

                          Lead Product(s) : Live Fecal Microbiota-jslm

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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