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Rebiotix"},{"orgOrder":0,"company":"Rebiotix","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Microorganism","year":"2020","type":"Inapplicable","leadProduct":"Rbx2660","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Rebiotix","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Rectal Enema","sponsorNew":"Rebiotix \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Rebiotix \/ Inapplicable"},{"orgOrder":0,"company":"Rebiotix","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Microorganism","year":"2022","type":"Inapplicable","leadProduct":"Rbx2660","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Liquid, Instillation","sponsorNew":"Ferring Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Ferring Pharmaceuticals \/ Inapplicable"}]

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                          01

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Adstiladrin (nadofaragene firadenovec) is an intravesical non-replicating gene therapy for adult patients with high-risk BCG-unresponsive NMIBC with CIS with or without papillary tumors.

                          Product Name : Adstiladrin

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 21, 2025

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Adstiladrin (nadofaragene firadenovec) is the first FDA-approved intravesical gene therapy for high-risk BCG-unresponsive NMIBC with carcinoma in situ, evaluated for adult patients.

                          Product Name : Adstiladrin

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 16, 2024

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Adstiladrin (nadofaragene firadenovec-vncg) is an FDA-approved gene therapy delivering a human IFNα2b gene to the bladder for treating BCG-unresponsive non-muscle invasive bladder cancer.

                          Product Name : Adstiladrin

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 24, 2024

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase IV

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : ADSTILADRIN® (nadofaragene firadenovec-vncg) is the first and only FDA-approved intravesical gene therapy for the treatment of adult patients with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer.

                          Product Name : Adstiladrin

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 09, 2023

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Adstiladrin (nadofaragene firadenovec-vncg) is the first and only FDA-approved non-replicating adenovirus vector-based therapy for the treatment of adult patients with high-risk BCG-unresponsive NMIBC with carcinoma in situ (CIS) with or without papillar...

                          Product Name : Adstiladrin

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 06, 2023

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Under the agreement, Royalty Pharma is acquiring a 5.1 percentage royalty on net sales of Adstiladrin (nadofaragene firadenovec-vncg), a gene therapy developed as a treatment for adult patients with BCG-unresponsive NMIBC, in the United States.

                          Product Name : Adstiladrin

                          Product Type : Cell and Gene therapy

                          Upfront Cash : $300.0 million

                          August 23, 2023

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Royalty Pharma

                          Deal Size : $500.0 million

                          Deal Type : Agreement

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                          07

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : SI-6603 (condoliase), which contains Condoliase as its active pharmaceutical ingredient, is intended to treat lumbar disc herniation via a single, direct intradiscal injection.

                          Product Name : SI-6603

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          May 26, 2023

                          Lead Product(s) : Condoliase

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Rekovelle (follitropin delta) is a follicle-stimulating hormone made from recombinant human DNA that is used to promote follicular development in females with ovarian failure, reproduction and fertility.

                          Product Name : Rekovelle

                          Product Type : Hormone

                          Upfront Cash : Inapplicable

                          March 14, 2023

                          Lead Product(s) : Follitropin Delta

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Phase IV

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Rebyota (live fecal microbiota-jslm) is the first and only microbiome-based treatment approved by the U.S. FDA to prevent recurrence of Clostridioides difficile (C. diff) infection in individuals 18 years of age and older.

                          Product Name : Rebyota

                          Product Type : Probiotic

                          Upfront Cash : Inapplicable

                          February 14, 2023

                          Lead Product(s) : Live Fecal Microbiota

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Adstiladrin, an intravesical therapy administered every three months, targets the patient’s own bladder wall cells to enhance the body’s natural defenses to fight cancer.

                          Product Name : Adstiladrin

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 16, 2022

                          Lead Product(s) : Nadofaragene Firadenovec

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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