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01

Peptide Therapy Summit
Not Confirmed
Peptide Therapy Summit
Not Confirmed

Details : The firibastat (originally named QGC001) product, a BAPAI candidate-drug, is a prodrug that delivers in the brain the EC33 product, a selective and specific inhibitor of Aminopeptidase A, thus preventing the production of Angiontensin III in the brain.

Product Name : QGC001

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

October 28, 2022

Lead Product(s) : Firibastat

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

Peptide Therapy Summit
Not Confirmed
Peptide Therapy Summit
Not Confirmed

Details : The aim of the study is to assess the efficacy and the safety of firibastat compared to ramipril. The primary endpoint is the change from baseline in Left Ventricle Ejection Fraction (LVEF) assessed by Cardiac Magnetic Resonance (CMR) after a three-month...

Product Name : QGC001

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

April 21, 2021

Lead Product(s) : Firibastat

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

Peptide Therapy Summit
Not Confirmed
Peptide Therapy Summit
Not Confirmed

Details : Phase III Pivotal REFRESH Study is part of firibastat’s Phase III clinical development and aims to assess long-term safety as well as the three-month efficacy after a single daily dose of firibastat 1000mg in treatment resistant hypertensive patients.

Product Name : QGC001

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

January 18, 2021

Lead Product(s) : Firibastat

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

Peptide Therapy Summit
Not Confirmed
Peptide Therapy Summit
Not Confirmed

Details : Under the terms of the agreement, Faran will receive the exclusive rights to market Firibastat for the treatment of difficult-to-treat / resistant hypertension in Greece.

Product Name : QGC001

Product Type : Other Small Molecule

Upfront Cash : $12.1 million

December 15, 2020

Lead Product(s) : Firibastat

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Faran

Deal Size : Undisclosed

Deal Type : Collaboration

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05

Peptide Therapy Summit
Not Confirmed
Peptide Therapy Summit
Not Confirmed

Details : Under the terms of the agreement, Xediton Pharmaceuticals will receive exclusive commercialization rights to firibastat for the treatment of difficult to treat/resistant hypertension in Canada.

Product Name : QGC001

Product Type : Other Small Molecule

Upfront Cash : $11.3 million

October 28, 2020

Lead Product(s) : Firibastat

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase III

Sponsor : Xediton Pharmaceuticals

Deal Size : Undisclosed

Deal Type : Licensing Agreement

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06

Peptide Therapy Summit
Not Confirmed
Peptide Therapy Summit
Not Confirmed

Details : Under the terms of the agreement, Qilu Pharmaceutical will receive the exclusive rights to market firibastat for the treatment of difficult-to-treat / resistant hypertension in China, including Hong Kong and Macau.

Product Name : QGC001

Product Type : Other Small Molecule

Upfront Cash : $50.0 million

October 19, 2020

Lead Product(s) : Firibastat

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase III

Sponsor : Qilu Pharmaceutical

Deal Size : Undisclosed

Deal Type : Licensing Agreement

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07

Peptide Therapy Summit
Not Confirmed
Peptide Therapy Summit
Not Confirmed

Details : First patient in the Company’s FRESH study (Firibastat in treatment-RESistant Hypertension) in difficult-to-treat(1) or resistant(2) hypertension. The study is being conducted jointly with its partner in Latin America, the Biolab Sanus Pharmaceutical l...

Product Name : QGC001

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

July 13, 2020

Lead Product(s) : Firibastat

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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