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(Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"First Wave BioPharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"First Wave BioPharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"First Wave BioPharma \/ Not Applicable"},{"orgOrder":0,"company":"First Wave BioPharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"Adrulipase","moa":"","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"First Wave BioPharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Enteric Capsule","sponsorNew":"First Wave BioPharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"First Wave BioPharma \/ Not Applicable"},{"orgOrder":0,"company":"First Wave BioPharma","sponsor":"Sanofi","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"FRANCE","productType":"Small molecule","year":"2023","type":"Licensing Agreement","leadProduct":"Capeserod","moa":"","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"First Wave BioPharma","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"","sponsorNew":"First Wave BioPharma \/ First Wave BioPharma","highestDevelopmentStatusID":"1","companyTruncated":"First Wave BioPharma \/ First Wave BioPharma"},{"orgOrder":0,"company":"First Wave BioPharma","sponsor":"ImmunogenX","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Merger","leadProduct":"Latiglutenase","moa":"","graph1":"Gastroenterology","graph2":"Phase II","graph3":"First Wave BioPharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"","sponsorNew":"First Wave BioPharma \/ First Wave BioPharma","highestDevelopmentStatusID":"8","companyTruncated":"First Wave BioPharma \/ First Wave BioPharma"},{"orgOrder":0,"company":"First Wave BioPharma","sponsor":"ImmunogenX","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Large molecule","year":"2023","type":"Merger","leadProduct":"Latiglutenase","moa":"","graph1":"Gastroenterology","graph2":"Phase II","graph3":"First Wave BioPharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"","sponsorNew":"First Wave BioPharma \/ First Wave BioPharma","highestDevelopmentStatusID":"8","companyTruncated":"First Wave BioPharma \/ First Wave BioPharma"},{"orgOrder":0,"company":"First Wave BioPharma","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Agreement","leadProduct":"Niclosamide","moa":"","graph1":"Gastroenterology","graph2":"Phase I\/ Phase II","graph3":"First Wave BioPharma","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Enema","sponsorNew":"First Wave BioPharma \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"First Wave BioPharma \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals by First Wave BioPharma

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Through acquisition, First Wave advances its lead product IMGX003 (latiglutenase) for treating celiac disease, currently under Phase II clinical trials.

                          Brand Name : IMGX003

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          March 14, 2024

                          Lead Product(s) : Latiglutenase

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Recipient : ImmunogenX

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Through the agreement, the company will prioritize the clinical development of FW-UP (niclosamide), currently undergoing Phase I/II clinical trial studies for the treatment of ulcerative colitis.

                          Brand Name : FW-UP

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 27, 2023

                          Lead Product(s) : Niclosamide

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Through the acquisition, First Wave will advance its lead product candidate IMGX003 (latiglutenase) for research & development and commercialization purposes. Currently, it is being evaluated in Phase II clinical trial studies for the treatment of Celiac...

                          Brand Name : IMGX003

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          December 18, 2023

                          Lead Product(s) : Latiglutenase

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Recipient : ImmunogenX

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Under the terms of the agreement, First Wave will receive from Sanofi an exclusive, global license for Capeserod, a selective 5-HT4 receptor partial agonist, which First Wave will repurpose and develop for gastrointestinal (GI) indications.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 14, 2023

                          Lead Product(s) : Capeserod

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Recipient : Sanofi

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : FW-EPI (adrulipase) is an oral administered, recombinant lipase enzyme, non-systemic biologic capsule for the treatment of EPI associated with CF and CP. It is designed to break up fat molecules in the digestive tract of EPI patients so that they can be ...

                          Brand Name : FW-EPI

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 13, 2023

                          Lead Product(s) : Adrulipase

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : FW-EPI (adrulipase) is an oral administered, recombinant lipase enzyme, non-systemic biologic capsule for the treatment of EPI associated with CF and CP. It is designed to break up fat molecules in the digestive tract of EPI patients so that they can be ...

                          Brand Name : FW-EPI

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 28, 2023

                          Lead Product(s) : Adrulipase

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : FW-EPI (adrulipase) is an oral administered, recombinant lipase enzyme, non-systemic biologic capsule for the treatment of EPI associated with CF and CP. It is designed to break up fat molecules in the digestive tract of EPI patients so that they can be ...

                          Brand Name : FW-EPI

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 13, 2023

                          Lead Product(s) : Adrulipase

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : FW-EPI (adrulipase) is an oral administered, recombinant lipase enzyme, non-systemic biologic capsule for the treatment of EPI associated with CF and CP. It is designed to break up fat molecules in the digestive tract of EPI patients so that they can be ...

                          Brand Name : FW-EPI

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 11, 2023

                          Lead Product(s) : Adrulipase

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : FW-EPI (adrulipase) is a recombinant lipase enzyme administered as an oral, non-systemic biologic capsule which is designed to break up fat molecules in the digestive tract of EPI patients for the treatment of EPI associated with CF and CP.

                          Brand Name : FW-EPI

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 25, 2023

                          Lead Product(s) : Adrulipase

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : FW-EPI (adrulipase) is a recombinant lipase enzyme administered as an oral, non-systemic biologic capsule which is designed to break up fat molecules in the digestive tract of EPI patients for the treatment of EPI associated with CF and CP.

                          Brand Name : FW-EPI

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 10, 2023

                          Lead Product(s) : Adrulipase

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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