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    [{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Seagen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Undisclosed","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Five Prime Therapeutics \/ Seagen","highestDevelopmentStatusID":"1","companyTruncated":"Five Prime Therapeutics \/ Seagen"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"FPA157","moa":"CCR8","graph1":"Oncology","graph2":"Preclinical","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Five Prime Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Five Prime Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"Cabiralizumab","moa":"||CSF-1 receptor","graph1":"Oncology","graph2":"Phase II","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Five Prime Therapeutics \/ Bristol Myers Squibb","highestDevelopmentStatusID":"8","companyTruncated":"Five Prime Therapeutics \/ Bristol Myers Squibb"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Amgen Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2021","type":"Acquisition","leadProduct":"Bemarituzumab","moa":"||FGFR2B","graph1":"Oncology","graph2":"Phase III","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Five Prime Therapeutics \/ Amgen Inc","highestDevelopmentStatusID":"10","companyTruncated":"Five Prime Therapeutics \/ Amgen Inc"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Amgen Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2021","type":"Acquisition","leadProduct":"Bemarituzumab","moa":"||FGFR2B","graph1":"Oncology","graph2":"Phase III","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Five Prime Therapeutics \/ Amgen Inc","highestDevelopmentStatusID":"10","companyTruncated":"Five Prime Therapeutics \/ Amgen Inc"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Cowen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2020","type":"Public Offering","leadProduct":"Bemarituzumab","moa":"FGFR2B","graph1":"Oncology","graph2":"Phase III","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Five Prime Therapeutics \/ Cowen","highestDevelopmentStatusID":"10","companyTruncated":"Five Prime Therapeutics \/ Cowen"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"5 Fluorouracil","moa":"||FGFR2B","graph1":"Oncology","graph2":"Phase III","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Five Prime Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Five Prime Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"5 Fluorouracil","moa":"||FGFR2B","graph1":"Oncology","graph2":"Phase III","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Five Prime Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Five Prime Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2021","type":"Inapplicable","leadProduct":"5 Fluorouracil","moa":"||FGFR2B","graph1":"Oncology","graph2":"Phase III","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Five Prime Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Five Prime Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Five Prime Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"Bemarituzumab","moa":"FGFR2B","graph1":"Oncology","graph2":"Phase III","graph3":"Five Prime Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Five Prime Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Five Prime Therapeutics \/ Inapplicable"}]

    Find Oncology Clinical Drug Pipeline Developments & Deals by Five Prime Therapeutics

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                            01

                            Five Prime Therapeutics

                            U.S.A arrow
                            AACR Annual meeting
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                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : Bemarituzumab,Calcium Folinate,Oxaliplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Amgen Inc

                            Deal Size : $1,900.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Amgen Successfully Completes Acquisition Of Five Prime Therapeutics

                            Details : Five Prime fits squarely within Amgen's leading oncology portfolio and includes bemarituzumab, a Phase 3 trial-ready, first-in-class program for gastric cancer, the third leading cause of cancer mortality worldwide.

                            Product Name : FPA144

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            April 16, 2021

                            Lead Product(s) : Bemarituzumab,Calcium Folinate,Oxaliplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Amgen Inc

                            Deal Size : $1,900.0 million

                            Deal Type : Acquisition

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                            02

                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : Bemarituzumab,Oxaliplatin,Calcium Folinate

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Amgen Inc

                            Deal Size : $1,900.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Amgen To Acquire Five Prime Therapeutics For $1.9 Billion in Cash

                            Details : Five Prime's lead asset, bemarituzumab, is a first-in-class, Phase 3 ready anti-FGFR2b antibody with positive data from a randomized, placebo-controlled Phase 2 study in frontline advanced gastric or gastroesophageal junction (GEJ) cancer.

                            Product Name : FPA144

                            Product Type : Antibody

                            Upfront Cash : $1,900.0 million

                            April 03, 2021

                            Lead Product(s) : Bemarituzumab,Oxaliplatin,Calcium Folinate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Amgen Inc

                            Deal Size : $1,900.0 million

                            Deal Type : Acquisition

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                            03

                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : Bemarituzumab,Fluorouracil,Calcium Folinate

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Five Prime Therapeutics Presents Results of Phase 2 FIGHT Trial at ASCO GI

                            Details : The FIGHT trial evaluated bemarituzumab plus chemotherapy vs placebo plus chemotherapy in patients with fibroblast growth factor receptor 2b-positive , non HER2+ frontline advanced gastric or GEJ cancer. All three efficacy endpoints met pre-specified sta...

                            Product Name : FPA144

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 15, 2021

                            Lead Product(s) : Bemarituzumab,Fluorouracil,Calcium Folinate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : Bemarituzumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Cowen

                            Deal Size : $5.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Five Prime Announces Proposed Public Offering of Common Stock

                            Details : Five Prime plans to use the net proceeds of the offering to fund ongoing clinical development of bemarituzumab and FPT155, to advance FPA157 through preclinical and into clinical development, to advance its late-stage research programs and for working ca...

                            Product Name : FPA144

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            November 11, 2020

                            Lead Product(s) : Bemarituzumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Cowen

                            Deal Size : $5.0 million

                            Deal Type : Public Offering

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                            05

                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : Bemarituzumab,Fluorouracil,Oxaliplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Five Prime Announces Bemarituzumab Plus Chemotherapy Demonstrates Significant Progression-Free and Overall Sur...

                            Details : All 3 efficacy endpoints in the Global Phase 2 FIGHT trial met pre-specified statistical significance. Bemarituzumab is a first-in-class therapeutic antibody targeting FGFR2b+ tumors found in approximately 30 percent of HER2- gastric cancers worldwide.

                            Product Name : FPA144

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            October 11, 2020

                            Lead Product(s) : Bemarituzumab,Fluorouracil,Oxaliplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : Bemarituzumab,Fluorouracil,Oxaliplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Five Prime to Present Phase 2 FIGHT Trial Results of Bemarituzumab at ASCO Gastrointestinal Cancers Virtual An...

                            Details : FIGHT trial met all three efficacy endpoints with bemarituzumab in combination with mFOLFOX6 chemotherapy providing statistically significant and clinically meaningful improvements in progression-free survival, overall survival, and objective response ra...

                            Product Name : FPA144

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 12, 2020

                            Lead Product(s) : Bemarituzumab,Fluorouracil,Oxaliplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Five Prime Therapeutics

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                            Lead Product(s) : Bemarituzumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Five Prime Therapeutics Announces Publication of the Phase 1 Bemarituzumab Study

                            Details : Phase 1 data illustrates the therapeutic potential of bemarituzumab as a novel approach to treating patients with FGFR2b-overexpressing gastric and gastroesophageal junction adenocarcinoma (GEA).

                            Product Name : FPA144

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 13, 2020

                            Lead Product(s) : Bemarituzumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Five Prime Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Undisclosed

                            Sponsor : Seagen

                            Deal Size : $300.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Five Prime Grabs $5M lifeline in Seattle Genetics ADC deal

                            Details : Five Prime granted Seattle Genetics an exclusive worldwide license to a family of monoclonal antibodies and Seattle Genetics will be responsible for R&D manufacturing and marketing of ADC products.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $5.0 million

                            February 19, 2020

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Undisclosed

                            Sponsor : Seagen

                            Deal Size : $300.0 million

                            Deal Type : Licensing Agreement

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                            09

                            Five Prime Therapeutics

                            U.S.A arrow
                            AACR Annual meeting
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                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : Cabiralizumab,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Five Prime Therapeutics Provides Update on Phase 2 Trial of Cabiralizumab Combined with Opdivo® in Pancreatic...

                            Details : Phase 2 Trial of cabiralizumab plus opdivo (nivolumab) with and without chemotherapy in advanced pancreatic cancer did not meet primary endpoint.

                            Product Name : FPA008

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 18, 2020

                            Lead Product(s) : Cabiralizumab,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Five Prime Therapeutics

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                            AACR Annual meeting
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                            AACR Annual meeting
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                            Lead Product(s) : FPA157

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Five Prime to Present First Preclinical Data of Anti-CCR8 Antibody FPA157 at Society for Immunotherapy of Canc...

                            Details : FPA157 is an antibody-dependent cell-mediated cytotoxicity (ADCC)-enhanced monoclonal antibody targeting CCR8 that is designed to deplete the T regulatory cell (Treg) population in the tumor microenvironment.

                            Product Name : FPA157

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 11, 2020

                            Lead Product(s) : FPA157

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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