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    [{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Cystic Fibrosis Foundation","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Partnership","leadProduct":"Undisclosed","moa":"","graph1":"Genetic Disease","graph2":"Discovery","graph3":"Flagship Pioneering","amount2":0.11,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Genetic Disease","amount2New":0.11,"dosageForm":"Dosage Strength\/Form","sponsorNew":"Flagship Pioneering \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"2","companyTruncated":"Flagship Pioneering \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Novo Nordisk","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Collaboration","leadProduct":"Undisclosed","moa":"","graph1":"Cardiology\/Vascular 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Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Abiologics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Financing","leadProduct":"Synteins-based Therapy","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Flagship Pioneering","amount2":0.050000000000000003,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"12","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"GSK","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Vaccine","year":"2024","type":"Collaboration","leadProduct":"Undisclosed","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Flagship 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    Find Clinical Drug Pipeline Developments & Deals by Flagship Pioneering

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                            01

                            Flagship Pioneering

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                            Lead Product(s) : AND-body Therapeutics

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Discovery Platform

                            Recipient : Ampersand Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Flagship Pioneering Signs Two Agreements Under Pfizer Strategic Partnership

                            Details : Under the collaboration, Ampersand's AND™ Platform will be used to identify programmed biologics for the treatment of obesity-related targets.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            November 20, 2024

                            Lead Product(s) : AND-body Therapeutics

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Discovery Platform

                            Recipient : Ampersand Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            02

                            Flagship Pioneering

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Recipient : Montai Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Flagship Announces Two New Agreements with Ampersand & Montai

                            Details : Under the collaboration, Montai's CONECTA™ AI platform will be used to identify small molecules directed to a potential Non-Small Cell Lung Cancer-related target.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            November 20, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Recipient : Montai Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            03

                            Flagship Pioneering

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Discovery

                            Sponsor : GSK

                            Deal Size : $7,200.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            GSK becomes Flagship's latest partner in $7B biobucks respiratory, immunology pact

                            Details : The Flagship collaborates with GSK to discover and develop a portfolio of future transformational medicines and vaccines for the treatment of respiratory and immunology diseases.

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : $150.0 million

                            July 29, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Discovery

                            Sponsor : GSK

                            Deal Size : $7,200.0 million

                            Deal Type : Collaboration

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                            04

                            Flagship Pioneering

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                            Lead Product(s) : Synteins-based Therapy

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Recipient : Abiologics

                            Deal Size : $50.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Flagship’s Abiologics sets sail with $50M for synthetic protein R&D

                            Details : The proceeds will advance company's platform and develop a diverse pipeline of medicines, Synteins, with an initial focus on oncology and immunology indications.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            July 23, 2024

                            Lead Product(s) : Synteins-based Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Recipient : Abiologics

                            Deal Size : $50.0 million

                            Deal Type : Financing

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                            05

                            Flagship Pioneering

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Discovery Platform

                            Recipient : ProFound Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Flagship Pioneering and ProFound Collaborate on First-in-Class Therapeutics for Obesity

                            Details : ProFound will deploy its proprietary ProFoundry Platform in collaboration with Pioneering Medicines' expertise to discover novel proteins and evaluate their therapeutic relevance for obesity.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 12, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Discovery Platform

                            Recipient : ProFound Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            Flagship Pioneering

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                            Lead Product(s) : tRNA Medicine

                            Therapeutic Area : Genetic Disease

                            Study Phase : Discovery Platform

                            Recipient : Alltrna

                            Deal Size : $109.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Alltrna Announces Series B Raise of $109 Million to Advance tRNA Medicines for Stop Codon Disease

                            Details : The financing will be used to advance the company's platform and first drug candidates towards the clinic for a first indication in Stop Codon Disease.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            August 09, 2023

                            Lead Product(s) : tRNA Medicine

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Discovery Platform

                            Recipient : Alltrna

                            Deal Size : $109.0 million

                            Deal Type : Series B Financing

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                            07

                            Flagship Pioneering

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                            Lead Product(s) : EDP2939

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Recipient : Evelo Biosciences

                            Deal Size : $25.5 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Evelo Biosciences Closes $25.5 Million Private Placement

                            Details : The company intends to use the net proceeds to fund the completion of the Company’s ongoing Phase 2a trial of EDP2939, an investigational orally delivered and gut-restricted bacterial extracellular vesicle being developed for the treatment of moderate ...

                            Brand Name : EDP2939

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            July 12, 2023

                            Lead Product(s) : EDP2939

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Recipient : Evelo Biosciences

                            Deal Size : $25.5 million

                            Deal Type : Private Placement

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                            08

                            Flagship Pioneering

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                            Flagship Pioneering

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Discovery

                            Recipient : Empress Therapeutics

                            Deal Size : $50.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Flagship Pioneering Unveils Empress Therapeutics to Revolutionize Drug Discovery by Applying the Power of Gene...

                            Details : The net proceeds will be used to support the development of Empress's proprietary Chemilogics™ product platform which creates potential small molecule medicines and the company's initial pipeline of drug candidates.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 21, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Discovery

                            Recipient : Empress Therapeutics

                            Deal Size : $50.0 million

                            Deal Type : Financing

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                            09

                            Flagship Pioneering

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                            Flagship Pioneering

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Discovery

                            Recipient : Metaphore Biotechnologies

                            Deal Size : $50.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Flagship Pioneering Launches Metaphore Biotechnologies to Unlock the Therapeutic Potential of Biomimicry

                            Details : The proceeds will advance Metaphore's MIMiC drug discovery platform and build its pipeline for autoimmune, metabolic or oncology indications. The MIMiC™ platform drives unprecedented insights into molecular interactions to design new biomolecules for t...

                            Brand Name : Undisclosed

                            Molecule Type : Undisclosed

                            Upfront Cash : Undisclosed

                            May 16, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Discovery

                            Recipient : Metaphore Biotechnologies

                            Deal Size : $50.0 million

                            Deal Type : Financing

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                            10

                            Flagship Pioneering

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery

                            Recipient : Charles River Laboratories International

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Charles River and Flagship’s Pioneering Medicines Enter Agreement Leveraging AI-Powered Logica with Aim of C...

                            Details : Under the agreement, Logica, an offering from Charles River and Valo Health will be deployed by Pioneering Medicines across a portfolio of targets with the aim of creating optimized small molecules that lead to novel therapies for unmet medical needs.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 16, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery

                            Recipient : Charles River Laboratories International

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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