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Find Clinical Drug Pipeline Developments & Deals by Flexion Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : This acquisition is a major milestone to build a robust offering of novel, non-opioid treatments to improve patient care along the neural pain pathway while simultaneously providing a complementary commercial asset in ZILRETTA for the treatment of OA kne...

                          Brand Name : Zilretta

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 11, 2021

                          Lead Product(s) : Triamcinolone Acetonide

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Pacira BioSciences

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Company to expand FX201 low dose and mid dose cohorts to include up to 20 additional patients in each treatment group. Clinical data from the first two cohorts indicate that FX201 appears to be generally safe and well-tolerated at the low and mid doses.

                          Brand Name : FX201

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          February 18, 2021

                          Lead Product(s) : Humantakinogene hadenovec

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Previously presented preclinical findings show FX301 provided greater sustained, post-operative analgesic effect with no significant impairment in motor function compared to liposomal bupivacaine and placebo.

                          Brand Name : FX301

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 05, 2020

                          Lead Product(s) : Funapide

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Five patients treated in first cohort of Phase 1 clinical trial evaluating the safety and tolerability of FX201; Drug Monitoring Committee (DMC) supported the initiation of the next dosing cohort.

                          Brand Name : FX201

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 08, 2020

                          Lead Product(s) : Humantakinogene hadenovec

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : New animal data show FX301 provided sustained, post-operative analgesic effect with no impairment in motor function compared to liposomal bupivacaine and placebo.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 27, 2020

                          Lead Product(s) : Funapide

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Under the terms of the agreement, Flexion will be solely responsible for the manufacture and supply of ZILRETTA to HK Tainuo for all clinical and commercial activities.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : $10.0 million

                          April 01, 2020

                          Lead Product(s) : Omadacycline

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : HK Tainuo

                          Deal Size : $42.5 million

                          Deal Type : Licensing Agreement

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