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    Find Clinical Drug Pipeline Developments & Deals by Foghorn Therapeutics

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                            01

                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-909

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Eli Lilly

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Doses First Patient with SMARCA2 Inhibitor For Solid Tumors

                            Details : FHD-909 is a first-in-class oral BRM selective inhibitor. It is being evaluated in preclinical studies for the treatment of BRG1 mutated non-small cell lung cancer.

                            Brand Name : FHD-909

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 10, 2024

                            Lead Product(s) : FHD-909

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Eli Lilly

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Foghorn Therapeutics

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                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-286,Cytarabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : BVF Partners

                            Deal Size : $110.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Foghorn Therapeutics Raises $110 Million Through Direct Offering to Advance Pipeline

                            Details : The net proceeds will be used to advance the clinical development of FHD-286, a selective, oral inhibitor of BRG1 and BRM, which is being evaluated in relapsed/refractory AML

                            Brand Name : FHD-286

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 22, 2024

                            Lead Product(s) : FHD-286,Cytarabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : BVF Partners

                            Deal Size : $110.0 million

                            Deal Type : Public Offering

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                            03

                            Foghorn Therapeutics

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                            Antibody Engineering
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                            Lead Product(s) : FHD-909

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Eli Lilly

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Provides Pipeline Update on FHD-909 BRM Selective Inhibitor

                            Details : FHD-909 is a first-in-class oral BRM selective inhibitor. It is being evaluated in preclinical studies for the treatment of BRG1 mutated non-small cell lung cancer.

                            Brand Name : FHD-909

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 08, 2024

                            Lead Product(s) : FHD-909

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Eli Lilly

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Foghorn Therapeutics

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                            Antibody Engineering
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                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-286,Cytarabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Therapeutics Announces First Patient Dosed in Phase 1 Combination Study of FHD-286 for Relapsed and/or...

                            Details : FHD-286 is a highly potent, selective, allosteric and orally available, small-molecule, enzymatic inhibitor of BRG1 and BRM, which is investigated for the treatment of relapsed and/or refractory acute myelogenous leukemia.

                            Brand Name : FHD-286

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 31, 2023

                            Lead Product(s) : FHD-286,Cytarabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Foghorn Therapeutics

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                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-286

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Therapeutics Announces Clinical Data from Phase 1 Study of FHD-286 in Metastatic Uveal Melanoma

                            Details : FHD-286 is a highly potent, selective, allosteric and orally available, small-molecule, enzymatic inhibitor of BRG1 and BRM, which is investigated for the treatment of Metastatic Uveal Melanoma.

                            Brand Name : FHD-286

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 28, 2023

                            Lead Product(s) : FHD-286

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-286

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Therapeutics Announces FDA Has Lifted Clinical Hold on Phase 1 Study of FHD-286 in Relapsed and/or Ref...

                            Details : FHD-286 is a highly potent, selective, allosteric and orally available, small-molecule, enzymatic inhibitor of BRG1 and BRM. FDA has lifted the clinical hold on the Phase 1 monotherapy dose escalation study of FHD-286 in AML and MDS.

                            Brand Name : FHD-286

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 05, 2023

                            Lead Product(s) : FHD-286

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Foghorn Therapeutics

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                            Antibody Engineering
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                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-609

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Therapeutics Provides an Update on FHD-609

                            Details : FHD-609 breaks down a protein called BRD9 that can turn on other groups of proteins and promote the growth of cancer cells. Stopping BRD9 from acting on these other proteins may stop the growth of new cancer cells.

                            Brand Name : FHD-609

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 24, 2023

                            Lead Product(s) : FHD-609

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Foghorn Therapeutics

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                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-286

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Therapeutics Highlights Recent Clinical and Research Progress and Provides Strategic Objectives for 20...

                            Details : FHD-286 is a highly potent, selective, allosteric and orally available, small-molecule, enzymatic inhibitor of BRG1 and BRM. In preclinical studies, FHD-286 has shown anti-tumor activity for broad range of malignancies.

                            Brand Name : FHD-286

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 09, 2023

                            Lead Product(s) : FHD-286

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Foghorn Therapeutics

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                            Antibody Engineering
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                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-286

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Therapeutics Announces New Preclinical Data for FHD-286 in AML to Be Presented at the American Society...

                            Details : FHD-286 is a highly potent, allosteric and orally available, small-molecule, enzymatic inhibitor of BRG1 and BRM, two highly similar proteins that are the ATPases, or the catalytic engines of the BAF complex, one of the key regulators within the chromati...

                            Brand Name : FHD-286

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 05, 2022

                            Lead Product(s) : FHD-286

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Foghorn Therapeutics

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                            Lead Product(s) : FHD-286,Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Foghorn Therapeutics to Present New Preclinical Data for BRG1/BRM Inhibitor FHD-286 in Combination with Anti-P...

                            Details : New preclinical data will be presented on FHD-286, a potent and selective BRG1/BRM inhibitor, which is currently in Phase 1 clinical trials for metastatic uveal melanoma and for relapsed and/or refractory acute myelogenous leukemia and myelodysplastic sy...

                            Brand Name : FHD-286

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 09, 2022

                            Lead Product(s) : FHD-286,Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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