Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Recipient : LoQus23 Therapeutics
Deal Size : $43.0 million
Deal Type : Series A Financing
LoQus23 Secures £35M to Advance Small Molecule Therapy for Huntington's Disease
Details : The proceeds from the financing will be primarily used to support the pre-clinical development and initial clinical studies of LoQus23's lead program, an allosteric small molecule MutSβ inhibitor.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 02, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Recipient : LoQus23 Therapeutics
Deal Size : $43.0 million
Deal Type : Series A Financing
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : IND Enabling
Recipient : Progentos Therapeutics
Deal Size : $65.0 million
Deal Type : Series A Financing
Progentos Therapeutics Closes $65 Million Series A Financing for Multiple Sclerosis
Details : The financing aims to fund the Progentos, which is developing first-in-class small molecules designed to induce remyelination of axons affected by multiple sclerosis.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 20, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Recipient : Progentos Therapeutics
Deal Size : $65.0 million
Deal Type : Series A Financing
Lead Product(s) : Emactuzumab
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : SynOx Therapeutics
Deal Size : $75.0 million
Deal Type : Series B Financing
Donesta Safety Study for Menopause Completes Treatment Phase
Details : The proceeds will be used to advance late-stage product Emactuzumab, SynOx's potentially best-in-class CSF-1(R) inhibiting monoclonal antibody for the treatment of Tenosynovial Giant Cell Tumour.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
April 22, 2024
Lead Product(s) : Emactuzumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : SynOx Therapeutics
Deal Size : $75.0 million
Deal Type : Series B Financing
Lead Product(s) : Idelalisib
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Recipient : Calluna Pharma
Deal Size : $81.1 million
Deal Type : Series A Financing
Two biotechs Merge to Form Calluna, with €75M in Hand to Focus on Immunotherapy Antibodies
Details : Calluna Pharma focuses on the clinical stage lead program CAL101, which is a monoclonal antibody that neutralizes the bioactivity of S100A4 & implements DAMP protein for idiopathic pulmonary fibrosis.
Brand Name : CAL101
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 22, 2024
Lead Product(s) : Idelalisib
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Recipient : Calluna Pharma
Deal Size : $81.1 million
Deal Type : Series A Financing
Lead Product(s) : KYN-5356
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : Kynexis Therapeutics
Deal Size : $62.1 million
Deal Type : Series A Financing
Kynexis Launched to Advance Precision Therapeutics for Brain Diseases
Details : Through the proceeds, Kynexis will advance its lead therapeutic candidate, KYN-5356, a potential first-in-class KAT-II inhibitor for the treatment of cognitive impairment associated with schizophrenia (CIAS), toward clinical development.
Brand Name : KYN-5356
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 07, 2023
Lead Product(s) : KYN-5356
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : Kynexis Therapeutics
Deal Size : $62.1 million
Deal Type : Series A Financing
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Recipient : Noema Pharma
Deal Size : $112.0 million
Deal Type : Series B Financing
Details : The proceeds of the Series B financing will be used to advance Noema Pharma's clinical-stage assets including its lead compound NOE-101 (basimglurant), an mGluR5 inhibitor which is being evaluated in Phase 2b clinical trials for severe pain in TN and sei...
Brand Name : NOE-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 07, 2023
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Recipient : Noema Pharma
Deal Size : $112.0 million
Deal Type : Series B Financing
Lead Product(s) : Olorofim
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Recipient : F2G Limited
Deal Size : $70.0 million
Deal Type : Financing
Details : The proceeds from the financing with Shionogi & Co., Ltd., will enable F2G to advance late-stage development and commercialization in the US of F901318 (olorofim), a novel oral antifungal therapy to treat invasive aspergillosis and other rare mold infect...
Brand Name : F901318
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 04, 2022
Lead Product(s) : Olorofim
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Recipient : F2G Limited
Deal Size : $70.0 million
Deal Type : Financing
Lead Product(s) : ARM210
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Recipient : ARMGO Pharma
Deal Size : $35.0 million
Deal Type : Series B Financing
Details : Proceeds will fund further clinical development of its lead asset, ARM210, for the treatment of catecholaminergic polymorphic ventricular tachycardia (CPVT) as well as other cardiac and skeletal muscle indications.
Brand Name : S48168
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 20, 2021
Lead Product(s) : ARM210
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Recipient : ARMGO Pharma
Deal Size : $35.0 million
Deal Type : Series B Financing
Lead Product(s) : ANV419
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Anaveon
Deal Size : $119.6 million
Deal Type : Series B Financing
Anaveon to raise CHF 110 million in oversubscribed Series B financing
Details : Proceeds from this financing will enable the Company to pursue multiple parallel Phase II programs in order to explore the full therapeutic potential of ANV419. ANV419, is designed to signal through the IL-2 beta/gamma receptor and overcome known challen...
Brand Name : ANV419
Molecule Type : Large molecule
Upfront Cash : Undisclosed
December 16, 2021
Lead Product(s) : ANV419
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Anaveon
Deal Size : $119.6 million
Deal Type : Series B Financing
Lead Product(s) : PJS-539
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PJS-539 is a potent, once daily, oral pill that inhibits attachment, infection and replication of SARS-CoV-2 and other RNA viruses to treat COVID-19.
Brand Name : PJS-539
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 06, 2021
Lead Product(s) : PJS-539
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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