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    [{"orgOrder":0,"company":"Forge Biologics","sponsor":"Perceptive Xontogeny Venture Fund","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Series A Financing","leadProduct":"FBX-101","moa":"","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Forge Biologics","amount2":0.040000000000000001,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0.040000000000000001,"dosageForm":"Intravenous Infusion","sponsorNew":"Forge Biologics \/ Perceptive Xontogeny Venture Fund","highestDevelopmentStatusID":"7","companyTruncated":"Forge Biologics \/ Perceptive Xontogeny Venture Fund"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"FBX-101","moa":"","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Intravenous infusion","sponsorNew":"Forge Biologics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Forge Biologics \/ Not Applicable"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"GentiBio","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Agreement","leadProduct":"Undisclosed","moa":"","graph1":"Immunology","graph2":"Preclinical","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Forge Biologics \/ GentiBio","highestDevelopmentStatusID":"4","companyTruncated":"Forge Biologics \/ GentiBio"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Solid Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Partnership","leadProduct":"SGT-003","moa":"","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"","sponsorNew":"Forge Biologics \/ Forge Biologics","highestDevelopmentStatusID":"7","companyTruncated":"Forge Biologics \/ Forge Biologics"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Ray Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Partnership","leadProduct":"Ray-001","moa":"","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Intravitreal","sponsorNew":"Forge Biologics \/ Forge Biologics","highestDevelopmentStatusID":"4","companyTruncated":"Forge Biologics \/ Forge Biologics"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"AAVrh.10-hGALC","moa":"GALC gene","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Forge Biologics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Forge Biologics \/ Not Applicable"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Drive Capital","pharmaFlowCategory":"D","therapeuticArea":"Technology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Series C Financing","leadProduct":"AAV-based Gene Therapy","moa":"","graph1":"Technology","graph2":"Undisclosed","graph3":"Forge Biologics","amount2":0.089999999999999997,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Technology","amount2New":0.089999999999999997,"dosageForm":"","sponsorNew":"Forge Biologics \/ Drive Capital","highestDevelopmentStatusID":"1","companyTruncated":"Forge Biologics \/ Drive Capital"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Myrtelle","pharmaFlowCategory":"D","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Partnership","leadProduct":"AAV-based TMPRSS3 Gene Therapy","moa":"","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"IND Enabling","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"","sponsorNew":"Forge Biologics \/ Myrtelle","highestDevelopmentStatusID":"5","companyTruncated":"Forge Biologics \/ Myrtelle"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Ray Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Collaboration","leadProduct":"RTx-015","moa":"","graph1":"Genetic Disease","graph2":"IND Enabling","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Forge Biologics \/ Forge Biologics","highestDevelopmentStatusID":"5","companyTruncated":"Forge Biologics \/ Forge Biologics"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"AAVrh.10-hGALC","moa":"GALC gene","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Forge Biologics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Forge Biologics \/ Not Applicable"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Eikonoklastes Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Partnership","leadProduct":"ET-101","moa":"","graph1":"Neurology","graph2":"Preclinical","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Forge Biologics \/ Forge Biologics","highestDevelopmentStatusID":"4","companyTruncated":"Forge Biologics \/ Forge Biologics"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Not Applicable","leadProduct":"FBX-101","moa":"","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Forge Biologics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Forge Biologics \/ Not Applicable"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Life Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Partnership","leadProduct":"Undisclosed","moa":"","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"","sponsorNew":"Forge Biologics \/ Life Biosciences","highestDevelopmentStatusID":"4","companyTruncated":"Forge Biologics \/ Life Biosciences"},{"orgOrder":0,"company":"Forge Biologics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"FBX-101","moa":"","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Forge Biologics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Forge Biologics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Forge Biologics \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Forge Biologics

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                            01

                            Forge Biologics

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                            Lead Product(s) : FBX-101

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Forge Biologics Reports FBX-101 Update in Krabbe Disease Identified by Newborn Screening

                            Details : FBX-101 is an adeno-associated viral serotype rh10 (AAVrh10) gene therapy. It is being evaluated in phase 1/2 clinical trials for the treatment of Krabbe Disease.

                            Brand Name : FBX-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 29, 2024

                            Lead Product(s) : FBX-101

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Forge Biologics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Ophthalmology

                            Study Phase : Preclinical

                            Sponsor : Life Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Life Biosciences and Forge Biologics Announce cGMP Manufacturing Partnership to Advance Development of Novel G...

                            Details : Forge will help to advance Life Bio’s partial epigenetic reprogramming platform to address aging-related diseases, including its lead program targeting ophthalmic indications by providing cGMP manufacturing and development services for its novel AAV ge...

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            May 08, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Preclinical

                            Sponsor : Life Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            03

                            Forge Biologics

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                            Lead Product(s) : FBX-101

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Forge Biologics Receives Priority Medicines (PRIME) Designation from the European Medicines Agency (EMA) for N...

                            Details : FBX-101 is an adeno-associated viral serotype rh10 gene therapy which delivers a functional copy of the GALC gene to cells in both the CNS and PNS. It has been shown to functionally correct the central and peripheral neuropathy associated with krabbe.

                            Brand Name : FBX-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 17, 2023

                            Lead Product(s) : FBX-101

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Forge Biologics

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                            Lead Product(s) : ET-101

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : Eikonoklastes Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Eikonoklastes Therapeutics and Forge Biologics Announce Viral Vector Contract Development and AAV Manufacturin...

                            Details : The partnership will advance Eikonoklastes’ AAV-based gene therapy, ET-101, into clinical trials for the treatment of patients with amyotrophic lateral sclerosis (ALS).

                            Brand Name : ET-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            November 29, 2022

                            Lead Product(s) : ET-101

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : Eikonoklastes Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            05

                            Forge Biologics

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                            Forge Biologics

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                            Lead Product(s) : AAVrh.10-hGALC

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Forge Biologics Announces Updated Positive Clinical Data in RESKUE, a Novel Phase 1/2 Gene Therapy Trial for P...

                            Details : Subjects treated with FBX-101 (AAVrh.10-hGALC) have shown increased galactocerebrosidase (GALC) enzyme activity in plasma and cerebrospinal fluid (CSF), normal white matter myelination and normalization of motor development in two children 90 days and 9 ...

                            Brand Name : FBX-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 11, 2022

                            Lead Product(s) : AAVrh.10-hGALC

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Forge Biologics

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                            Lead Product(s) : RTx-015

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Recipient : Ray Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Ray Therapeutics and Forge Biologics Expand Their Viral Vector cGMP Partnership to Encompass Plasmid DNA Manuf...

                            Details : Forge will provide research-grade and GMP-Pathway plasmid manufacturing services, in addition to adeno-associated viral vector (AAV) process development, scale-up engineering, and cGMP manufacturing services for Ray Therapeutics’ program, RTx-015.

                            Brand Name : RTx-015

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            October 10, 2022

                            Lead Product(s) : RTx-015

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Recipient : Ray Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Forge Biologics

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                            Lead Product(s) : AAV-based TMPRSS3 Gene Therapy

                            Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                            Study Phase : IND Enabling

                            Sponsor : Myrtelle

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Myrtelle and Forge Biologics Announce Viral Vector and Plasmid DNA cGMP Manufacturing Partnership

                            Details : Forge will provide research-grade and GMP-Pathway plasmid manufacturing services as well as cGMP adeno-associated viral (AAV) process development and scale-up manufacturing services for Myrtelle’s program, Myr-201 (gene therapy delivery of a therapeuti...

                            Brand Name : Myr-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            October 03, 2022

                            Lead Product(s) : AAV-based TMPRSS3 Gene Therapy

                            Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                            Highest Development Status : IND Enabling

                            Sponsor : Myrtelle

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            08

                            Forge Biologics

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                            Forge Biologics

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                            Lead Product(s) : AAV-based Gene Therapy

                            Therapeutic Area : Technology

                            Study Phase : Undisclosed

                            Sponsor : Drive Capital

                            Deal Size : $90.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Forge Biologics Announces $90 Million Series C Financing to Expand Client Offerings and Add Services to Enhanc...

                            Details : The Company will use the funding to expand client offerings, including proprietary technologies, manufacturing systems, cell lines, and additional services to bolster its end-to-end manufacturing platform.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 12, 2022

                            Lead Product(s) : AAV-based Gene Therapy

                            Therapeutic Area : Technology

                            Highest Development Status : Undisclosed

                            Sponsor : Drive Capital

                            Deal Size : $90.0 million

                            Deal Type : Series C Financing

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                            09

                            Forge Biologics

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                            Forge Biologics

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                            Lead Product(s) : AAVrh.10-hGALC

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Forge Reports Positive Clinical Data on Brain Development and Motor Function from the RESKUE Novel Phase 1/2 G...

                            Details : FBX-101 is an adeno-associated viral serotype rh10 (AAVrh.10-hGALC) gene therapy that is typically delivered after a hematopoietic stem cell transplant. FBX-101 delivers a functional copy of the GALC gene to cells in both the central and peripheral nervo...

                            Brand Name : FBX-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            August 30, 2022

                            Lead Product(s) : AAVrh.10-hGALC

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Forge Biologics

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                            Lead Product(s) : Ray-001

                            Therapeutic Area : Genetic Disease

                            Study Phase : Preclinical

                            Recipient : Ray Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Ray Therapeutics and Forge Biologics Announce Viral Vector Contract Development and cGMP Manufacturing Partner...

                            Details : Ray-001 is intended for use in treating patients with retinitis pigmentosa (RP). Optogenetics is a promising approach that has the potential to restore useful vision to visually-impaired and blind individuals.

                            Brand Name : Ray-001

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            March 01, 2022

                            Lead Product(s) : Ray-001

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Preclinical

                            Recipient : Ray Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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