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    [{"orgOrder":0,"company":"Forte Biosciences","sponsor":"","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Merger","leadProduct":"FB-401","moa":"TLR5","graph1":"Dermatology","graph2":"Phase II","graph3":"Forte Biosciences","amount2":0.029999999999999999,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0.029999999999999999,"dosageForm":"Topical","sponsorNew":"Forte Biosciences \/ ","highestDevelopmentStatusID":"8","companyTruncated":"Forte Biosciences \/ "},{"orgOrder":0,"company":"Forte Biosciences","sponsor":"Denovo Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Acquisition","leadProduct":"Vocimagene amiretrorepvec","moa":"","graph1":"Oncology","graph2":"Discovery","graph3":"Forte 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    Find Clinical Drug Pipeline Developments & Deals by Forte Biosciences

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                            01

                            Forte Biosciences

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                            Lead Product(s) : FB102

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : OrbiMed

                            Deal Size : $53.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Forte Biosciences Raises $53M to Advance FB102 in Autoimmune Disorders

                            Details : The proceeds will support the clinical advancement of FB102, a proprietary anti-CD122 monoclonal antibody therapeutic candidate with potentially broad autoimmune and autoimmune-related indications.

                            Brand Name : FB102

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            November 20, 2024

                            Lead Product(s) : FB102

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : OrbiMed

                            Deal Size : $53.0 million

                            Deal Type : Private Placement

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                            02

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                            Lead Product(s) : FB-102

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Alger

                            Deal Size : $25.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Forte Biosciences, Inc. Announces $25 Million Financing and R&D Update for FB-102

                            Details : The net financing will support the advancement of FB-102, which targets CD-122 and has demonstrated potentially best in class activity in graft versus host disease (GvHD).

                            Brand Name : FB-102

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            August 01, 2023

                            Lead Product(s) : FB-102

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Alger

                            Deal Size : $25.0 million

                            Deal Type : Financing

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                            03

                            Forte Biosciences

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                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clinical Trial of FB-401 For the Treatment of Atopic Dermatitis Fails to Meet Statistical Significance

                            Details : Phase 2 clinical trial of FB-401 for the treatment of atopic dermatitis failed to meet statistical significance for the primary endpoint of EASI-50 (the proportion of patients with at least a 50% improvement in atopic dermatitis disease severity as measu...

                            Brand Name : FB-401

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 02, 2021

                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Forte Biosciences

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                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Forte Biosciences Shares Clinical Trial of FB-401 For the Treatment of Atopic Dermatitis Fails to Meet Statist...

                            Details : The primary endpoint of EASI-50 was achieved by 58% of subjects on FB-401 compared to 60% of subjects on placebo. Positive trends were observed in key secondary endpoints including EASI-90 with 27.6% of subjects in the active arm achieving the EASI-90 en...

                            Brand Name : FB-401

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 02, 2021

                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Forte Biosciences

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                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Forte Biosciences, Inc. Announces the FDA Has Granted Fast Track Designation to FB-401 for the Treatment of At...

                            Details : FB-401 is a topically applied live biotherapeutic consisting of specifically selected strains of commensal Roseomonas mucosa and has demonstrated excellent tolerability and significant improvement in atopic dermatitis disease activity in both adults and ...

                            Brand Name : FB-401

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 26, 2020

                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

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                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Forte Biosciences Dosed First Patient in the Clinical Trial of FB-401 for the Treatment of Children and Adults...

                            Details : The multi-center, placebo controlled clinical trial of FB-401 is expected to enroll approximately 124 pediatric, adolescent and adult subjects aged 2 years of age and older with atopic dermatitis (AD).

                            Brand Name : FB-401

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 29, 2020

                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

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                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Forte Biosciences, Inc. Announces Issuance of New U.S. Patent

                            Details : Forte Biosciences announced the issuance of its seventh U.S. patent (10,682,379), broadening protection to include methods for culturing gram negative bacteria from the skin.

                            Brand Name : FB-401

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 18, 2020

                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

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                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Forte Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Forte Biosciences, Inc. Announces Closing of Merger With Tocagen

                            Details : As per the merger agreement, stockholders of Forte have become the majority owners of Tocagen, and the operations of Forte and Tocagen have combined.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 15, 2020

                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Forte Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            09

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                            Lead Product(s) : Vocimagene amiretrorepvec

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : Denovo Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Denovo Biopharma To Acquire Tocagen's Entire Replicating Gene Therapy Platform and Related Assets

                            Details : The acquisition includes Tocagen's retroviral replicating vector platform, investigational gene therapy and drug regimen for oncology: Toca 511 and Toca FC and several other development programs.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            April 28, 2020

                            Lead Product(s) : Vocimagene amiretrorepvec

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : Denovo Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            10

                            Forte Biosciences

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                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor :

                            Deal Size : $25.0 million

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Tocagen and Forte Biosciences Announce Merger

                            Details : The merged company will focus on advancing Forte's clinical program in inflammatory skin diseases, including atopic dermatitis.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 19, 2020

                            Lead Product(s) : FB-401

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor :

                            Deal Size : $25.0 million

                            Deal Type : Merger

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