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    [{"orgOrder":0,"company":"Pfizer Inc","sponsor":"Pfizer Inc","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2020","type":"Series C Financing","leadProduct":"Fosmanogepix","moa":"Gwt1","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Pfizer Inc","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.050000000000000003,"dosageForm":"","sponsorNew":"Pfizer Inc \/ Pfizer","highestDevelopmentStatusID":"8","companyTruncated":"Pfizer Inc \/ Pfizer"},{"orgOrder":0,"company":"Pfizer Inc","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Fosmanogepix","moa":"Gwt1","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Pfizer 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    Find Clinical Drug Pipeline Developments & Deals for Fosmanogepix

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                            01

                            Basilea Pharmaceutica

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                            Basilea Pharmaceutica

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Basilea Initiates Phase 3 Study with Antifungal Fosmanogepix for Candidemia

                            Details : PF-07842805 (fosmanogepix), a potential first-in-class, clinical-stage broad-spectrum antifungal treatment candidate for Candidemia, including Candida auris, and invasive mold infections.

                            Brand Name : PF-07842805

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 23, 2024

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Basilea Pharmaceutica

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : BARDA

                            Deal Size : $29.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Basilea Partners with BARDA To Develop Novel Antifungals, Gets Initial Funding

                            Details : The funding aims to support the development of Basilea’s clinical stage first-in-class antifungal, APX-001 (fosmanogepix), which is being investigated for the treatment of invasive candidiasis.

                            Brand Name : APX-001

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 19, 2024

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : BARDA

                            Deal Size : $29.0 million

                            Deal Type : Funding

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                            03

                            Pfizer Inc

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Basilea Pharmaceutica

                            Deal Size : $147.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Basilea Announces Acquisition of Fosmanogepix, a Phase-3-Ready Broad-Spectrum Antifungal

                            Details : Basilea has acquired the rights to PF-07842805 (fosmanogepix), a potential first-in-class, clinical-stage broad-spectrum antifungal treatment candidate for the treatment of Candidemia, including Candida auris, and invasive mold infections.

                            Brand Name : PF-07842805

                            Molecule Type : Small molecule

                            Upfront Cash : $37.0 million

                            November 13, 2023

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Basilea Pharmaceutica

                            Deal Size : $147.0 million

                            Deal Type : Acquisition

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                            04

                            Pfizer Inc

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                            Pfizer Inc

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Pfizer Inc

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Pfizer Acquires Amplyx Pharmaceuticals

                            Details : With this acquisition Pfizer adds Amplyx’s lead compound, Fosmanogepix (APX001) to its pipeline and in addition to this Pfizer has secured ownership of Amplyx's early-stage pipeline that includes potential antiviral (MAU868) and antifungal (APX2039) th...

                            Brand Name : APX001

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            April 28, 2021

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Pfizer Inc

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            05

                            Pfizer Inc

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                            Pfizer Inc

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Amplyx to Present New Clinical and Preclinical Data for its Two Lead Programs at Upcoming Scientific Conferenc...

                            Details : At IDWeek 2020, positive data from the Phase 2 clinical trial evaluating fosmanogepix, a novel IV and oral Gwt1 inhibitor, in patients with candidemia will be presented during an oral session at the American Society of Nephrology (ASN) Kidney Week 2020.

                            Brand Name : APX001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 16, 2020

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Pfizer Inc

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                            Pfizer Inc

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Amplyx Touts Upbeat Readout from a Small PhII Study for Lead Antifungal

                            Details : Topline data from the study indicated fosmanogepix's success rate of 80 percent, meeting the primary endpoint and paving the way to a pivotal trial ahead.

                            Brand Name : APX001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 20, 2020

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Pfizer Inc

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                            Pfizer Inc

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Pfizer Inc

                            Deal Size : $53.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            With Bucks From Pfizer Added To Their New Round, Amplyx Steers a Tricky Course Through PhII and a Global Pande...

                            Details : Amplyx plans to use this Series C funds to advance the clinical development of the company’s two product candidates, fosmanogepix (APX001) and MAU868 for the treatment of life-threatening fungal infections and BK Virus.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 19, 2020

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Pfizer Inc

                            Deal Size : $53.0 million

                            Deal Type : Series C Financing

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                            08

                            Pfizer Inc

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Amplyx Pharmaceuticals Advances Development of Novel Antifungal, Fosmanogepix

                            Details : Amplyx has advanced development of its lead program, fosmanogepix (APX001). Enrollment has been completed in a Phase 2 trial evaluating the safety and efficacy of fosmanogepix for the treatment of infections caused by Candida.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 19, 2020

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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