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Find Clinical Drug Pipeline Developments & Deals for Fosmanogepix

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                          Top Deals by Deal Size (USD bn)

                          01

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : PF-07842805 (fosmanogepix), a potential first-in-class, clinical-stage broad-spectrum antifungal treatment candidate for Candidemia, including Candida auris, and invasive mold infections.

                          Product Name : APX001

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 23, 2024

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The funding aims to support the development of Basilea’s clinical stage first-in-class antifungal, APX-001 (fosmanogepix), which is being investigated for the treatment of invasive candidiasis.

                          Product Name : APX001

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          September 19, 2024

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : BARDA

                          Deal Size : $29.0 million

                          Deal Type : Funding

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                          03

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Basilea has acquired the rights to PF-07842805 (fosmanogepix), a potential first-in-class, clinical-stage broad-spectrum antifungal treatment candidate for the treatment of Candidemia, including Candida auris, and invasive mold infections.

                          Product Name : APX001

                          Product Type : Other Small Molecule

                          Upfront Cash : $37.0 million

                          November 13, 2023

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Basilea Pharmaceutica

                          Deal Size : $147.0 million

                          Deal Type : Acquisition

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                          04

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : With this acquisition Pfizer adds Amplyx’s lead compound, Fosmanogepix (APX001) to its pipeline and in addition to this Pfizer has secured ownership of Amplyx's early-stage pipeline that includes potential antiviral (MAU868) and antifungal (APX2039) th...

                          Product Name : APX001

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          April 28, 2021

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Pfizer Inc

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          05

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : At IDWeek 2020, positive data from the Phase 2 clinical trial evaluating fosmanogepix, a novel IV and oral Gwt1 inhibitor, in patients with candidemia will be presented during an oral session at the American Society of Nephrology (ASN) Kidney Week 2020.

                          Product Name : APX001

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 16, 2020

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Topline data from the study indicated fosmanogepix's success rate of 80 percent, meeting the primary endpoint and paving the way to a pivotal trial ahead.

                          Product Name : APX001

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 20, 2020

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Amplyx plans to use this Series C funds to advance the clinical development of the company’s two product candidates, fosmanogepix (APX001) and MAU868 for the treatment of life-threatening fungal infections and BK Virus.

                          Product Name : APX001

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          May 19, 2020

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Pfizer Inc

                          Deal Size : $53.0 million

                          Deal Type : Series C Financing

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                          08

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Amplyx has advanced development of its lead program, fosmanogepix (APX001). Enrollment has been completed in a Phase 2 trial evaluating the safety and efficacy of fosmanogepix for the treatment of infections caused by Candida.

                          Product Name : APX001

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 19, 2020

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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