Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Lefitolimod,Fostemsavir,10-1074
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MGN1703 (lefitolimod) is synthetic TLR9 agonist of the double-stem loop immunomodulators or dSLIM family where multiple CG-motifs are embedded into a stable, covalently closed double stem-loop DNA molecule harboring only natural phosphodiester bonds betw...
Brand Name : MGN1703
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 21, 2023
Lead Product(s) : Lefitolimod,Fostemsavir,10-1074
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostemsavir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : GSK
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Study findings showed that people living with multidrug-resistant HIV-1 treated for approximately five years with Rukobia (fostemsavir)-based regimens experienced durable virologic response and continued clinically meaningful improvement in CD4+ cell cou...
Brand Name : Rukobia
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 29, 2022
Lead Product(s) : Fostemsavir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : GSK
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostemsavir,Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ViiV Healthcare Announces US FDA Approval for Rukobia (fostemsavir)
Details : In a phase III study, a majority (60%) of heavily treatment-experienced adults randomized to receive Rukobia with an optimized background therapy achieved and maintained viral suppression through 96 weeks, addressing a critical unmet need.
Brand Name : Rukobia
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 02, 2020
Lead Product(s) : Fostemsavir,Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostemsavir,10-1074
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Rockefeller University
Deal Size : Undisclosed
Deal Type : Collaboration
Celldex Therapeutics Announces $1.7 Million Milestone Payment from Rockefeller University
Details : Celldex utilized their internal capabilities in production cell line development, process development and GMP manufacturing to support clinical development of 3BNC117 and 10-1074.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : $1.7 million
March 03, 2020
Lead Product(s) : Fostemsavir,10-1074
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Rockefeller University
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Fostemsavir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : This application seeks approval of fostemsavir, used in combination with other antiretrovirals, for the treatment of adults with multidrug-resistant HIV-1 infection.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 10, 2020
Lead Product(s) : Fostemsavir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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