Lead Product(s) : Fostroxacitabine Bralpamide,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Hallberg Management AB
Deal Size : $12.3 million
Deal Type : Private Placement
Medivir Carries Out a Directed Share Issue of Approx. SEK 20 Million
Details : Medivir is focusing on the development of MIV-818 (fostroxacitabine bralpamide), a pro-drug designed to selectively treat hepatocellular carcinoma (HCC).
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 22, 2024
Lead Product(s) : Fostroxacitabine Bralpamide,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Hallberg Management AB
Deal Size : $12.3 million
Deal Type : Private Placement
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Quotient Sciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Quotient Sciences Supports Medivir with Updated Formulation of Fostrox
Details : MIV-818 (fostroxacitabine bralpamide) is DNA inhibitor. It is being evaluated under phase 1/2 clinical development in combination with Lenvima (lenvatinib) for the treatment of hepatocellular carcinoma.
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 27, 2023
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Quotient Sciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostroxacitabine Bralpamide
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Fostrox (fostroxacitabine bralpamide) is an oral nucleotide DNA polymerase inhibitor. It is being developed for the treatment of patients with hepatocellular carcinoma (HCC).
Brand Name : Fostrox
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 27, 2023
Lead Product(s) : Fostroxacitabine Bralpamide
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MIV-818 (fostroxacitabine bralpamide) is an orally active troxacitabine-based nucleotide prodrug, which is investigated in with fostrox in combination with Lenvima for the treatment of primary liver cancer.
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 25, 2023
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MIV-818 (fostroxacitabine bralpamide) is an orally active troxacitabine-based nucleotide prodrug, which is investigated in with fostrox in combination with Lenvima for the treatment of primary liver cancer.
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 05, 2023
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MIV-818 (fostroxacitabine bralpamide) is an orally active troxacitabine-based nucleotide prodrug, which is investigated in with fostrox in combination with Lenvima for the treatment of primary liver cancer.
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 04, 2023
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MIV-818 (fostroxacitabine bralpamide) is an orally active troxacitabine-based nucleotide prodrug, which is investigated for the treatment of primary liver cancer.
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 14, 2023
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Medivir's Patent Application for Fostrox Approved in China
Details : MIV-818 (fostroxacitabine bralpamide) is an orally active troxacitabine-based nucleotide prodrug, which is investigated for the treatment of primary liver cancer.
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 19, 2023
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostroxacitabine Bralpamide,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MIV-818 (fostroxacitabine bralpamide) is an orally active troxacitabine-based nucleotide prodrug. Its active metabolite troxacitabine triphosphate (TRX-TP) is then incorporated into rapidly dividing cancer cell's DNA, thereby causing DNA damage and cance...
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 14, 2023
Lead Product(s) : Fostroxacitabine Bralpamide,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Medivir Has Determined the Recommended Phase 2 Dose for Fostrox in Combination with Lenvima In HCC
Details : MIV-818 (fostroxacitabine bralpamide) is an orally active troxacitabine-based nucleotide prodrug. Its active metabolite troxacitabine triphosphate (TRX-TP) is then incorporated into rapidly dividing cancer cell's DNA, thereby causing DNA damage and cance...
Brand Name : MIV-818
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 20, 2023
Lead Product(s) : Fostroxacitabine Bralpamide,Lenvatinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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