Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : RJVA-001
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Fractyl Unveils Data On Rejuva® GLP-1 Gene Therapy in Diabetes Model
Details : RJVA-001 is the Company’s first GLP-1 gene therapy candidate to emerge from the Rejuva platform, setting the stage for a potentially transformative approach for metabolic diseases (obesity and T2D).
Brand Name : RJVA-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
March 12, 2024
Lead Product(s) : RJVA-001
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AAV-Delivered Pancreatic Gene Therapy
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Fractyl Nominates RJVA-001 as First Candidate in Its Rejuva® GLP-1 Gene Therapy Platform
Details : RJVA-001 is the first GLP-1 pancreatic gene therapy (GLP1 PGTx) candidate, which is being evaluated in preclinical studies for the treatment of Type 2 Diabetes (T2D).
Brand Name : RJVA-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 05, 2024
Lead Product(s) : AAV-Delivered Pancreatic Gene Therapy
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AAV-based Pancreatic Gene Therapy
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : BofA Securities
Deal Size : Undisclosed
Deal Type : Public Offering
Hoping its GLP-1 gene therapy can beat Wegovy, Fractyl plans IPO
Details : The net proceeds will be used to fund the continued preclinical development of our Rejuva, a GLP-1-based pancreatic gene therapy candidate, for treatment across the spectrum of type 2 diabetes and obesity.
Brand Name : Rejuva
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 15, 2023
Lead Product(s) : AAV-based Pancreatic Gene Therapy
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : BofA Securities
Deal Size : Undisclosed
Deal Type : Public Offering
Lead Product(s) : Pancreatic Gene Therapy
Therapeutic Area : Genetic Disease
Study Phase : Discovery
Sponsor : Michigan Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims to explore mechanisms of metabolic improvement and weight loss from an intrapancreatic gene therapy leveraging GLP-1-based transgenes for long-duration treatment of type 2 diabetes (T2D) and obesity.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 16, 2023
Lead Product(s) : Pancreatic Gene Therapy
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery
Sponsor : Michigan Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Pancreatic GLP-1 Gene Therapy
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Fractyl Health is developing not only an AAV vector platform, but also local delivery devices and methods to potentially enable Pancreatic GLP-1 Gene Therapy.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 05, 2022
Lead Product(s) : Pancreatic GLP-1 Gene Therapy
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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