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Find Clinical Drug Pipeline Developments & Deals by Fractyl Health

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : RJVA-001 is the Company’s first GLP-1 gene therapy candidate to emerge from the Rejuva platform, setting the stage for a potentially transformative approach for metabolic diseases (obesity and T2D).

                          Brand Name : RJVA-001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 12, 2024

                          Lead Product(s) : RJVA-001

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : RJVA-001 is the first GLP-1 pancreatic gene therapy (GLP1 PGTx) candidate, which is being evaluated in preclinical studies for the treatment of Type 2 Diabetes (T2D).

                          Brand Name : RJVA-001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          January 05, 2024

                          Lead Product(s) : AAV-Delivered Pancreatic Gene Therapy

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The net proceeds will be used to fund the continued preclinical development of our Rejuva, a GLP-1-based pancreatic gene therapy candidate, for treatment across the spectrum of type 2 diabetes and obesity.

                          Brand Name : Rejuva

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 15, 2023

                          Lead Product(s) : AAV-based Pancreatic Gene Therapy

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Preclinical

                          Sponsor : BofA Securities

                          Deal Size : Undisclosed

                          Deal Type : Public Offering

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The collaboration aims to explore mechanisms of metabolic improvement and weight loss from an intrapancreatic gene therapy leveraging GLP-1-based transgenes for long-duration treatment of type 2 diabetes (T2D) and obesity.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 16, 2023

                          Lead Product(s) : Pancreatic Gene Therapy

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Discovery

                          Sponsor : Michigan Medicine

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Fractyl Health is developing not only an AAV vector platform, but also local delivery devices and methods to potentially enable Pancreatic GLP-1 Gene Therapy.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 05, 2022

                          Lead Product(s) : Pancreatic GLP-1 Gene Therapy

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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