[{"orgOrder":0,"company":"Arrivent","sponsor":"Hillhouse Capital Group","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2021","type":"Series A Financing","leadProduct":"Furmonertinib","moa":"EGFR","graph1":"Oncology","graph2":"Approved","graph3":"Arrivent","amount2":0.14999999999999999,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0.14999999999999999,"dosageForm":"Oral","sponsorNew":"Arrivent \/ Hillhouse Capital Group","highestDevelopmentStatusID":"12","companyTruncated":"Arrivent \/ Hillhouse Capital Group"},{"orgOrder":0,"company":"Arrivent","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Furmonertinib","moa":"pan-EGFR mutant","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Arrivent \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Not Applicable"},{"orgOrder":0,"company":"Abbisko Therapeutics","sponsor":"Shanghai Allist Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Licensing Agreement","leadProduct":"ABK3376","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Abbisko Therapeutics","amount2":0.19,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.19,"dosageForm":"","sponsorNew":"Abbisko Therapeutics \/ Shanghai Allist Pharmaceuticals","highestDevelopmentStatusID":"4","companyTruncated":"Abbisko Therapeutics \/ Shanghai Allist Pharmaceuticals"},{"orgOrder":0,"company":"Arrivent","sponsor":"Sofinnova","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Series B Financing","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0.16,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.16,"dosageForm":"","sponsorNew":"Arrivent \/ Sofinnova","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Sofinnova"},{"orgOrder":0,"company":"InnoCare Pharma","sponsor":"Arrivent","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Collaboration","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"InnoCare Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"InnoCare Pharma \/ Arrivent","highestDevelopmentStatusID":"6","companyTruncated":"InnoCare Pharma \/ Arrivent"},{"orgOrder":0,"company":"InnoCare Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"InnoCare Pharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"InnoCare Pharma \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"InnoCare Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Arrivent","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Arrivent \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Not Applicable"},{"orgOrder":0,"company":"Arrivent","sponsor":"Goldman Sachs & Co.","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Public Offering","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0.17999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.17999999999999999,"dosageForm":"Tablet","sponsorNew":"Arrivent \/ Goldman Sachs & Co.","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Goldman Sachs & Co."},{"orgOrder":0,"company":"Arrivent","sponsor":"Goldman Sachs & Co.","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Public Offering","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0.14000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.17999999999999999,"dosageForm":"Tablet","sponsorNew":"Arrivent \/ Goldman Sachs & Co.","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Goldman Sachs & Co."},{"orgOrder":0,"company":"InnoCare Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"InnoCare Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"InnoCare Pharma \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"InnoCare Pharma \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals for Furmonertinib

Menu
Xls
Filters Filter
×
FILTER:
filter
Company Name
    filter

    Year

      filter

      DEALS // DEV.

        filter

        Country

          filter
          Sponsor
            filter

            Therapeutic Area

              filter

              Study Phase

                filter

                Deal Type

                  filter

                  Product Type

                    filter

                    Dosage Form

                      filter

                      Lead Product

                        filter

                        Target

                          Loading...

                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : ICP-189 is a potent and selective oral allosteric inhibitor of SHP2, which is being evaluated in combiation with furmonertinib for the treatment of advanced or metastatic non-small cell lung cancer.

                          Brand Name : ICP-189

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 28, 2024

                          Lead Product(s) : ICP-189,Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          blank

                          02

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : Proceeds will support NDA approval for furmonertinib, a novel oral EGFR kinase inhibitor with broad activity across EGFR mutations.

                          Brand Name : AST2818

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 25, 2024

                          Lead Product(s) : Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Goldman Sachs & Co.

                          Deal Size : $175.0 million

                          Deal Type : Public Offering

                          blank

                          03

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : The net proceeds will be used for the clinical development of (furmonertinib), which focuses on EGFR mutant-selective tyrosine kinase inhibitors that are developed for NSCLC patients.

                          Brand Name : AST2818

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 22, 2024

                          Lead Product(s) : Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Goldman Sachs & Co.

                          Deal Size : $135.7 million

                          Deal Type : Public Offering

                          blank

                          04

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : AST2818 (furmonertinib) is an oral, small molecule, highly brain-penetrant, pan-EGFR mutant inhibitor that targets both classical (exon 19 deletion and L858R) and atypical EGFR mutations, including exon 20 insertion mutations as well as HER2 exon 20 inse...

                          Brand Name : AST2818

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 30, 2023

                          Lead Product(s) : Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          blank

                          05

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : ICP-189 is a potent and selective oral allosteric inhibitor of SHP2, developed by InnoCare for the treatment of solid tumors as a single agent and/or in combination in combination with furmonertinib, a highly brain-penetrant, broadly active mutation-sele...

                          Brand Name : ICP-189

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 13, 2023

                          Lead Product(s) : ICP-189,Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          blank

                          06

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : Under the agreement, InnoCare and ArriVent will jointly evaluate the anti-tumor activity and safety of ICP-189, a novel SHP2 allosteric inhibitor, combined with furmonertinib, a highly brain-penetrant, broadly active mutation-selective EGFR inhibitor, in...

                          Brand Name : ICP-189

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 13, 2023

                          Lead Product(s) : ICP-189,Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Arrivent

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          blank

                          07

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : The net proceedings will be used to support pivotal Phase 3 and additional studies with the Company’s lead product candidate AST2818 (furmonertinib), a highly brain penetrant, mutant-specific EGFR kinase inhibitor.

                          Brand Name : AST2818

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 27, 2023

                          Lead Product(s) : Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Sofinnova

                          Deal Size : $155.0 million

                          Deal Type : Series B Financing

                          blank

                          08

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : The licensed small-molecule antagonist of EGFR ABK3376 is a pre-clinical candidate developed by Abbisko Therapeutics' proprietary drug discovery platform, which is a novel, highly potent, selective, and brain-penetrating new-generation EGFR inhibitor.

                          Brand Name : ABK3376

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 01, 2023

                          Lead Product(s) : ABK3376,Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Shanghai Allist Pharmaceuticals

                          Deal Size : $187.9 million

                          Deal Type : Licensing Agreement

                          blank

                          09

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : AST2818 (furmonertinib) is an oral, small molecule, highly brain-penetrant, pan-EGFR mutant inhibitor that targets both classical (exon 19 deletion and L858R) and atypical EGFR mutations, including exon 20 insertion mutations as well as HER2 exon 20 inse...

                          Brand Name : AST2818

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 05, 2022

                          Lead Product(s) : Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          blank

                          10

                          Skin Aging & Challenges
                          Not Confirmed
                          Skin Aging & Challenges
                          Not Confirmed

                          Details : Allist Pharma received approval for furmonertinib in EGFR T790M mutation-positive locally advanced or metastatic non-small-cell lung cancer (NSCLC) indications in China in March 2021.

                          Brand Name : AST2818

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 30, 2021

                          Lead Product(s) : Furmonertinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Hillhouse Capital Group

                          Deal Size : $150.0 million

                          Deal Type : Series A Financing

                          blank