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    [{"orgOrder":0,"company":"Arrivent","sponsor":"Hillhouse Capital Group","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2021","type":"Series A Financing","leadProduct":"Furmonertinib","moa":"EGFR","graph1":"Oncology","graph2":"Approved","graph3":"Arrivent","amount2":0.14999999999999999,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0.14999999999999999,"dosageForm":"Oral","sponsorNew":"Arrivent \/ Hillhouse Capital Group","highestDevelopmentStatusID":"12","companyTruncated":"Arrivent \/ Hillhouse Capital Group"},{"orgOrder":0,"company":"Arrivent","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Furmonertinib","moa":"pan-EGFR mutant","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Arrivent \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Not Applicable"},{"orgOrder":0,"company":"Abbisko Therapeutics","sponsor":"Shanghai Allist Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Licensing Agreement","leadProduct":"ABK3376","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Abbisko Therapeutics","amount2":0.19,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.19,"dosageForm":"","sponsorNew":"Abbisko Therapeutics \/ Shanghai Allist Pharmaceuticals","highestDevelopmentStatusID":"4","companyTruncated":"Abbisko Therapeutics \/ Shanghai Allist Pharmaceuticals"},{"orgOrder":0,"company":"Arrivent","sponsor":"Sofinnova","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Series B Financing","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0.16,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.16,"dosageForm":"","sponsorNew":"Arrivent \/ Sofinnova","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Sofinnova"},{"orgOrder":0,"company":"InnoCare Pharma","sponsor":"Arrivent","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Collaboration","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"InnoCare Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"InnoCare Pharma \/ Arrivent","highestDevelopmentStatusID":"6","companyTruncated":"InnoCare Pharma \/ Arrivent"},{"orgOrder":0,"company":"InnoCare Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"InnoCare Pharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"InnoCare Pharma \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"InnoCare Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Arrivent","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Arrivent \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Not Applicable"},{"orgOrder":0,"company":"Arrivent","sponsor":"Goldman Sachs & Co.","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Public Offering","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0.17999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.17999999999999999,"dosageForm":"Tablet","sponsorNew":"Arrivent \/ Goldman Sachs & Co.","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Goldman Sachs & Co."},{"orgOrder":0,"company":"Arrivent","sponsor":"Goldman Sachs & Co.","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Public Offering","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Arrivent","amount2":0.14000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.17999999999999999,"dosageForm":"Tablet","sponsorNew":"Arrivent \/ Goldman Sachs & Co.","highestDevelopmentStatusID":"10","companyTruncated":"Arrivent \/ Goldman Sachs & Co."},{"orgOrder":0,"company":"InnoCare Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Furmonertinib","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"InnoCare Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"InnoCare Pharma \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"InnoCare Pharma \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Furmonertinib

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                            01

                            InnoCare Pharma

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                            Lead Product(s) : ICP-189,Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            InnoCare Doses First Patient In Study Of ICP-189 Combined With Furmonertinib

                            Details : ICP-189 is a potent and selective oral allosteric inhibitor of SHP2, which is being evaluated in combiation with furmonertinib for the treatment of advanced or metastatic non-small cell lung cancer.

                            Brand Name : ICP-189

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 28, 2024

                            Lead Product(s) : ICP-189,Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Arrivent

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                            Arrivent

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                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Goldman Sachs & Co.

                            Deal Size : $175.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            ArriVent Announces Pricing of Upsized Initial Public Offering

                            Details : Proceeds will support NDA approval for furmonertinib, a novel oral EGFR kinase inhibitor with broad activity across EGFR mutations.

                            Brand Name : AST2818

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 25, 2024

                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Goldman Sachs & Co.

                            Deal Size : $175.0 million

                            Deal Type : Public Offering

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                            03

                            Arrivent

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                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Goldman Sachs & Co.

                            Deal Size : $135.7 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Arrivent Unveils $135M IPO Pricing to get Furmonertinib to FDA

                            Details : The net proceeds will be used for the clinical development of (furmonertinib), which focuses on EGFR mutant-selective tyrosine kinase inhibitors that are developed for NSCLC patients.

                            Brand Name : AST2818

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 22, 2024

                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Goldman Sachs & Co.

                            Deal Size : $135.7 million

                            Deal Type : Public Offering

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                            04

                            Arrivent

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                            Arrivent

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                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            ArriVent Receives FDA Breakthrough Therapy Designation for Furmonertinib for First-Line Treatment of Advanced ...

                            Details : AST2818 (furmonertinib) is an oral, small molecule, highly brain-penetrant, pan-EGFR mutant inhibitor that targets both classical (exon 19 deletion and L858R) and atypical EGFR mutations, including exon 20 insertion mutations as well as HER2 exon 20 inse...

                            Brand Name : AST2818

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 30, 2023

                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            InnoCare Pharma

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                            InnoCare Pharma

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                            Lead Product(s) : ICP-189,Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            InnoCare Announces Approval of Clinical Trial of SHP2 Inhibitor ICP-189 in Combination with EGFR Inhibitor Fur...

                            Details : ICP-189 is a potent and selective oral allosteric inhibitor of SHP2, developed by InnoCare for the treatment of solid tumors as a single agent and/or in combination in combination with furmonertinib, a highly brain-penetrant, broadly active mutation-sele...

                            Brand Name : ICP-189

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 13, 2023

                            Lead Product(s) : ICP-189,Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            InnoCare Pharma

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                            Lead Product(s) : ICP-189,Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Arrivent

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            InnoCare and ArriVent Announce Clinical Development Collaboration

                            Details : Under the agreement, InnoCare and ArriVent will jointly evaluate the anti-tumor activity and safety of ICP-189, a novel SHP2 allosteric inhibitor, combined with furmonertinib, a highly brain-penetrant, broadly active mutation-selective EGFR inhibitor, in...

                            Brand Name : ICP-189

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 13, 2023

                            Lead Product(s) : ICP-189,Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Arrivent

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Arrivent

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                            Arrivent

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                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Sofinnova

                            Deal Size : $155.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            ArriVent Biopharma Closes $155 Million Oversubscribed Series B Financing

                            Details : The net proceedings will be used to support pivotal Phase 3 and additional studies with the Company’s lead product candidate AST2818 (furmonertinib), a highly brain penetrant, mutant-specific EGFR kinase inhibitor.

                            Brand Name : AST2818

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            March 27, 2023

                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Sofinnova

                            Deal Size : $155.0 million

                            Deal Type : Series B Financing

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                            08

                            Abbisko Therapeutics

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                            Abbisko Therapeutics

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                            Lead Product(s) : ABK3376,Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Shanghai Allist Pharmaceuticals

                            Deal Size : $187.9 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Shanghai's Abbisko Out-Licenses EGFR Candidate in Potentially Nine-Figure Deal

                            Details : The licensed small-molecule antagonist of EGFR ABK3376 is a pre-clinical candidate developed by Abbisko Therapeutics' proprietary drug discovery platform, which is a novel, highly potent, selective, and brain-penetrating new-generation EGFR inhibitor.

                            Brand Name : ABK3376

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            March 01, 2023

                            Lead Product(s) : ABK3376,Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Shanghai Allist Pharmaceuticals

                            Deal Size : $187.9 million

                            Deal Type : Licensing Agreement

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                            09

                            Arrivent

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                            Arrivent

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                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            ArriVent Biopharma Announces First Patient Enrolled in Global Phase 1b Trial of Furmonertinib in Advanced or M...

                            Details : AST2818 (furmonertinib) is an oral, small molecule, highly brain-penetrant, pan-EGFR mutant inhibitor that targets both classical (exon 19 deletion and L858R) and atypical EGFR mutations, including exon 20 insertion mutations as well as HER2 exon 20 inse...

                            Brand Name : AST2818

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 05, 2022

                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Arrivent

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                            Arrivent

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                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Hillhouse Capital Group

                            Deal Size : $150.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            ArriVent Biopharma Launches With Up to $150M in Series A Financing and Strategic Licensing Agreement for Clini...

                            Details : Allist Pharma received approval for furmonertinib in EGFR T790M mutation-positive locally advanced or metastatic non-small-cell lung cancer (NSCLC) indications in China in March 2021.

                            Brand Name : AST2818

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 30, 2021

                            Lead Product(s) : Furmonertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Hillhouse Capital Group

                            Deal Size : $150.0 million

                            Deal Type : Series A Financing

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