Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The primary endpoint of the NEPTUNE study was not achieved. Patients given OV101 showed a 0.7 point improvement in CGI-I-AS over baseline while placebo also showed a 0.8 point improvement in CGI-I-AS.
Brand Name : OV101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 01, 2020
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Short hairpin RNA,Gaboxadol
Therapeutic Area : Genetic Disease
Study Phase : Undisclosed
Sponsor : University of Connecticut
Deal Size : Undisclosed
Deal Type : Collaboration
Ovid and UConn Enter Strategic Research Collaboration
Details : Ovid to collaborate with renowned molecular geneticist and Angelman syndrome expert Stormy J. Chamberlain, Ph.D., to advance a short hairpin RNA (shRNA)-based therapeutic with the goal of addressing the underlying genetic cause of Angelman syndrome.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 23, 2020
Lead Product(s) : Short hairpin RNA,Gaboxadol
Therapeutic Area : Genetic Disease
Highest Development Status : Undisclosed
Sponsor : University of Connecticut
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Angelini Pharma
Deal Size : $232.0 million
Deal Type : Licensing Agreement
Details : Angelini Pharma obtains exclusive development, manufacturing and commercialization rights to OV101 for the treatment of Angelman syndrome in the European Union and other countries in the European Economic Area, and also Switzerland, Turkey, the United Ki...
Brand Name : OV101
Molecule Type : Small molecule
Upfront Cash : $20.0 million
July 13, 2020
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Angelini Pharma
Deal Size : $232.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OV101 is believed to be the only delta (δ)-selective GABAA receptor agonist in development and is currently being evaluated in the Company’s pivotal Phase 3 NEPTUNE trial in Angelman syndrome, with topline results expected in the fourth quarter of 202...
Brand Name : OV101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 19, 2020
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The presentation will highlight data from the pivotal Phase 3 NEPTUNE trial investigating OV101 (gaboxadol) in Angelman syndrome.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 08, 2020
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : OV101 produced statistically significant reductions in behavioral and functional symptoms in individuals with Fragile X syndrome and met the study’s primary objective of safety and tolerability.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 07, 2020
Lead Product(s) : Gaboxadol
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
LOOKING FOR A SUPPLIER?