Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Aridis Meets Primary and Secondary Endpoints in Phase 2a Study of AR-501 in Cystic Fibrosis Patients
Details : AR-501 is a novel inhaled formulation of gallium citrate with broad-spectrum anti-infective activity involving iron acquisition and metabolism, is being developed to treat chronic lung infections in cystic fibrosis (CF) patients.
Brand Name : AR-501
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 13, 2023
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
New Approaches to Treating Infections in Cystic Fibrosis Patients - AR 501 Phase 2 Trial Update
Details : AR-501 is a novel inhaled formulation of gallium citrate with broad-spectrum anti-infective activity involving iron acquisition and metabolism, is being developed to treat chronic lung infections in cystic fibrosis (CF) patients.
Brand Name : AR-501
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 17, 2023
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Cystic Fibrosis Foundation
Deal Size : $12.5 million
Deal Type : Funding
CF Foundation Invests Up to $4.85 Million in Aridis Pharmaceuticals for Testing of Anti-Infective
Details : AR-501 is a novel, small molecule and an inhalable form of gallium citrate, which acts as an iron analog to starve bacteria of iron. Gallium is believed to inhibit multiple iron-dependent synthetic and metabolic pathways required for pathogenicity.
Brand Name : AR-501
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 12, 2022
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Cystic Fibrosis Foundation
Deal Size : $12.5 million
Deal Type : Funding
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AR-501 (gallium citrate) is an inhalable broad-spectrum anti-infective currently under development for controlling debilitating chronic lung infections in cystic fibrosis (CF) patients.
Brand Name : AR-501
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 30, 2022
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Aridis Announces Agreement with the FDA on Updated Phase 2 Clinical Trial Design for AR-501
Details : FDA also concurred with the Company's proposal to expand the originally planned Phase 2a protocol design into a Phase 2a/2b study of Company's AR-501 for the treatment of chronic lung infections associated with cystic fibrosis (CF).
Brand Name : AR-501
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 08, 2020
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AR-501 is being developed as a once-per-week dosing regimen that is self-administered using a hand-held nebulizer device. Phase 1 portion of the Phase 1/2a trial, 48 healthy volunteers were treated with either single or multiple weekly dose regimens with...
Brand Name : AR-501
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 22, 2020
Lead Product(s) : Gallium Citrate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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